MNDA Activators
MNDA (Myeloid Cell Nuclear Differentiation Antigen) Activators are a class of small molecules or compounds that have garnered significant attention in the field of molecular biology and cellular research. These activators are specifically designed to modulate the expression and activity of the MNDA gene, which encodes for the Myeloid Cell Nuclear Differentiation Antigen. MNDA is a protein primarily found in myeloid cells, a type of white blood cell involved in the immune response. It plays a crucial role in regulating various cellular processes, particularly those related to the immune system and inflammation.
The mechanism of MNDA activation typically involves the promotion of MNDA gene expression and the enhancement of its protein function within myeloid cells. By activating MNDA, these compounds can influence the differentiation and maturation of myeloid cells, ultimately impacting their immune-related functions. MNDA Activators have gained significance due to their potential in deciphering the intricate network of immune responses and inflammation regulation. Researchers are particularly interested in studying the downstream effects of MNDA activation, including its impact on cytokine production, immune cell signaling, and overall immune system homeostasis.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid can directly affect the expression of MNDA through influencing myeloid cell differentiation. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Cholecalciferol can indirectly activate MNDA by modulating immune responses and influencing myeloid cell differentiation. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone indirectly activates MNDA by influencing the differentiation and function of myeloid cells. | ||||||
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $325.00 $632.00 $1428.00 $2450.00 $400.00 | 32 | |
This active form of vitamin D indirectly activates MNDA by promoting monocyte differentiation into macrophages. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin can indirectly activate MNDA by elevating cAMP levels, impacting myeloid cell differentiation. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA indirectly activates MNDA by influencing myeloid cell differentiation through protein kinase C activation. | ||||||