Date published: 2026-4-13

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MKP-1 Antibodies

Santa Cruz Biotechnology delivers a wide array of MKP-1 monoclonal antibodies for research focused on understanding MKP-1's role in cellular processes. Multiple applications are supported, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA).MKP-1, or Mitogen-Activated Protein Kinase Phosphatase 1, is a critical regulator of MAPK signaling pathways, which are involved in cell proliferation, differentiation, and response to stress. By dephosphorylating MAPKs, MKP-1 plays a vital role in modulating cellular responses to various stimuli, making it an important focus in cancer research and inflammation studies. Understanding MKP-1 function can provide insights into therapeutic targets for diseases where MAPK signaling is dysregulated. Research has shown that MKP-1 expression levels can significantly impact cellular stress responses and inflammatory pathways. Recent studies have highlighted MKP-1's potential as a therapeutic target in various disease models. Investigating MKP-1's regulatory mechanisms has revealed its crucial role in maintaining cellular homeostasis. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of MKP-1's role in health and disease.

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MKP-1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MKP-1/DUSP1 Antibody (E-6)

sc-373841mouse IgG2b κ321-365 (m)WB, IP, IF, ELISAm, r, h
26
(9)

MKP-1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MKP-1/DUSP1 Double Nickase Plasmid (h)

sc-400243-NIChGene KnockoutPuromycin0
(0)

MKP-1/DUSP1 Double Nickase Plasmid (h2)

sc-400243-NIC-2hGene KnockoutPuromycin0
(0)

MKP-1/DUSP1 CRISPR/Cas9 KO Plasmid (m)

sc-422507mGene KnockoutGFP0
(0)

MKP-1/DUSP1 Double Nickase Plasmid (m)

sc-422507-NICmGene KnockoutPuromycin0
(0)

MKP-1/DUSP1 Double Nickase Plasmid (m2)

sc-422507-NIC-2mGene KnockoutPuromycin0
(0)

MKP-1 CRISPR Activation Products

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MKP-1/DUSP1 CRISPR Activation Plasmid (h)

sc-400243-ACThGene ActivationPuro, Blast, Hygro0
(0)

MKP-1/DUSP1 CRISPR Activation Plasmid (h2)

sc-400243-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

MKP-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MKP-1/DUSP1 siRNA (h)

sc-35937hGene SilencingN/A
26
(1)

MKP-1/DUSP1 siRNA (h2)

sc-44312hGene SilencingN/A
1
(0)

MKP-1/DUSP1 shRNA Plasmid (h)

sc-35937-SHhGene SilencingPuromycin
26
(1)

MKP-1/DUSP1 shRNA Plasmid (h2)

sc-44312-SHhGene SilencingPuromycin
1
(0)

MKP-1/DUSP1 shRNA (h) Lentiviral Particles

sc-35937-VhGene SilencingPuromycin
26
(1)

MKP-1/DUSP1 shRNA (h2) Lentiviral Particles

sc-44312-VhGene SilencingPuromycin
1
(0)

MKP-1/DUSP1 siRNA (m)

sc-35938mGene SilencingN/A
11
(0)

MKP-1/DUSP1 shRNA Plasmid (m)

sc-35938-SHmGene SilencingPuromycin
11
(0)

MKP-1/DUSP1 shRNA (m) Lentiviral Particles

sc-35938-VmGene SilencingPuromycin
11
(0)

MKP-1/DUSP1 siRNA (bovine)

sc-270515bovineGene SilencingN/A
1
(0)

MKP-1/DUSP1 shRNA Plasmid (bovine)

sc-270515-SHbovineGene SilencingPuromycin
1
(0)

MKP-1/DUSP1 shRNA (bovine) Lentiviral Particles

sc-270515-VbovineGene SilencingPuromycin
1
(0)