MFAP1A Inhibitors
MFAP1A inhibitors as a chemical class are not established due to the protein's role in structural constitution and involvement in mRNA splicing rather than a more typical enzymatic function. Compounds that have been listed are associated with the inhibition of processes related to the function of MFAP1A, such as extracellular matrix formation and mRNA splicing, rather than directly inhibiting the activity of MFAP1A itself.
These compounds are found in various chemical classes with diverse mechanisms of action. For example, beta-aminopropionitrile and disulfiram affect lysyl oxidase activity, which is critical for collagen cross-linking in the extracellular matrix, whereas pladienolide B and isoginkgetin target the splicing machinery, which is essential for the post-transcriptional modification of pre-mRNA. Despite their varied mechanisms, all these compounds can influence cellular processes that MFAP1A is predicted to be involved in, thereby offering indirect modes of inhibition.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
3-Aminopropionitrile | 151-18-8 | sc-266473 | 1 g | $104.00 | ||
Inhibits lysyl oxidase, which is involved in cross-linking collagen fibers, potentially affecting the stability of the extracellular matrix to which MFAP1A contributes. | ||||||
Halofuginone | 55837-20-2 | sc-507290 | 100 mg | $1775.00 | ||
Inhibits collagen type I synthesis and could alter the extracellular matrix composition, indirectly affecting MFAP1A. | ||||||
Penicillamine | 52-67-5 | sc-205795 sc-205795A | 1 g 5 g | $46.00 $96.00 | ||
Reduces cross-linking of collagen by chelating copper, which is a cofactor for lysyl oxidase; this could influence the integrity of the extracellular matrix involving MFAP1A. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $53.00 $89.00 | 7 | |
Inhibits lysyl oxidase by chelating copper, potentially altering the extracellular matrix structure and affecting MFAP1A indirectly. | ||||||
Pladienolide B | 445493-23-2 | sc-391691 sc-391691B sc-391691A sc-391691C sc-391691D sc-391691E | 0.5 mg 10 mg 20 mg 50 mg 100 mg 5 mg | $299.00 $5699.00 $11099.00 $25500.00 $66300.00 $2875.00 | 63 | |
A spliceosome inhibitor that disrupts mRNA splicing; could indirectly affect the splicing of mRNA relevant to MFAP1A. | ||||||
Isoginkgetin | 548-19-6 | sc-507430 | 5 mg | $225.00 | ||
A pre-mRNA splicing inhibitor that could indirectly affect the splicing of mRNA relevant to MFAP1A. | ||||||
Madrasin | 374913-63-0 | sc-507563 | 100 mg | $750.00 | ||
A splicing inhibitor that affects spliceosome assembly, potentially altering mRNA splicing processes involving MFAP1A. | ||||||
Herbimycin A | 70563-58-5 | sc-3516 sc-3516A | 100 µg 1 mg | $277.00 $1532.00 | 13 | |
A tyrosine kinase inhibitor that may affect signaling pathways involved in extracellular matrix regulation and thus indirectly influence MFAP1A. | ||||||