Date published: 2025-10-6

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ME1 Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of ME1 Antibodies for investigating malic enzyme 1 (ME1) in various biological processes. ME1 Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Malic enzyme 1 (ME1) plays a crucial role in cellular metabolism, particularly in the conversion of malate to pyruvate, which is essential for energy production and biosynthesis. ME1 actively participates in regulating NADPH levels, which impacts fatty acid synthesis and antioxidant defense mechanisms. Research has shown that ME1 expression levels can vary significantly across different tissue types and cellular conditions. Understanding ME1 function is vital for elucidating its implications in metabolic disorders and cancer development. Recent studies have highlighted ME1's potential as a therapeutic target in various disease states. Ongoing research continues to uncover new aspects of ME1's biological significance and regulatory mechanisms. Santa Cruz Biotechnology monoclonal antibodies for ME1 enable researchers to advance scientific understanding of cellular metabolism and disease mechanisms.

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ME1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

ME1 Antibody (C-6)

sc-365891mouse IgG1 κ34-80 (h)WB, IP, IF, ELISAm, r, h
3
(2)

ME1 Antibody (99.1)

sc-100569mouse IgG1 κ1-573 (h)WB, IP, IF, IHC(P), ELISAm, r, h
10
(5)

ME1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ME1 CRISPR/Cas9 KO Plasmid (h)

sc-401587hGene KnockoutGFP0
(0)

ME1 HDR Plasmid (h)

sc-401587-HDRhHomology Directed RepairPuromycin0
(0)

ME1 Double Nickase Plasmid (h)

sc-401587-NIChGene KnockoutPuromycin0
(0)

ME1 Double Nickase Plasmid (h2)

sc-401587-NIC-2hGene KnockoutPuromycin0
(0)

ME1 CRISPR/Cas9 KO Plasmid (m)

sc-421687mGene KnockoutGFP0
(0)

ME1 HDR Plasmid (m)

sc-421687-HDRmHomology Directed RepairPuromycin0
(0)

ME1 Double Nickase Plasmid (m)

sc-421687-NICmGene KnockoutPuromycin0
(0)

ME1 Double Nickase Plasmid (m2)

sc-421687-NIC-2mGene KnockoutPuromycin0
(0)

ME1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ME1 CRISPR Activation Plasmid (h)

sc-401587-ACThGene ActivationPuro, Blast, Hygro0
(0)

ME1 CRISPR Activation Plasmid (h2)

sc-401587-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

ME1 Lentiviral Activation Particles (h)

sc-401587-LAChGene ActivationPuro, Blast, Hygro0
(0)

ME1 Lentiviral Activation Particles (h2)

sc-401587-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

ME1 CRISPR Activation Plasmid (m)

sc-421687-ACTmGene ActivationPuro, Blast, Hygro0
(0)

ME1 CRISPR Activation Plasmid (m2)

sc-421687-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

ME1 Lentiviral Activation Particles (m)

sc-421687-LACmGene ActivationPuro, Blast, Hygro0
(0)

ME1 Lentiviral Activation Particles (m2)

sc-421687-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

ME1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ME1 siRNA (h)

sc-95470hGene SilencingN/A0
(0)

ME1 shRNA Plasmid (h)

sc-95470-SHhGene SilencingPuromycin0
(0)

ME1 shRNA (h) Lentiviral Particles

sc-95470-VhGene SilencingPuromycin0
(0)

ME1 siRNA (m)

sc-149342mGene SilencingN/A
1
(0)

ME1 shRNA Plasmid (m)

sc-149342-SHmGene SilencingPuromycin
1
(0)

ME1 shRNA (m) Lentiviral Particles

sc-149342-VmGene SilencingPuromycin
1
(0)