Date published: 2025-9-10

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MDGA2 Activators

MDGA2 activators represent a class of chemical compounds designed to modulate the activity of MDGA2 (MAM domain-containing glycosylphosphatidylinositol anchor protein 2), a cell surface protein with a significant presence in the nervous system. MDGA2 plays a crucial role in various aspects of neural development, particularly in processes related to cell adhesion, neural circuit formation, and synaptic plasticity. As a glycosylphosphatidylinositol (GPI)-anchored protein, MDGA2's functions are intricately linked to the regulation of synaptic connectivity and neural circuitry.

These activators are meticulously engineered to interact with MDGA2, potentially influencing its cellular functions. By targeting MDGA2, these compounds offer a means to delve into the intricate mechanisms governing neural development, synaptic plasticity, and the formation of neural circuits. Research focused on MDGA2 activators contributes to our understanding of the complex regulatory pathways underlying crucial neuronal processes, providing valuable insights into cellular physiology and the orchestration of fundamental events in the nervous system. Further investigation is warranted to uncover the precise mechanisms of action and potential biological consequences associated with MDGA2 activation, enhancing our knowledge of the molecular processes that underlie neural development and connectivity in the nervous system.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Retinoic acid regulates gene expression during neural development and may induce MDGA2 expression as part of this process.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

Forskolin raises cAMP levels, which can affect various signaling pathways, potentially influencing MDGA2 expression.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium is involved in developmental signaling pathways and may affect the expression of genes like MDGA2.

Valproic Acid

99-66-1sc-213144
10 g
$85.00
9
(1)

Valproic acid, through its HDAC inhibitory effect, can modulate gene expression, possibly affecting MDGA2.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

PMA activates protein kinase C, which could influence gene expression related to neuronal development, including MDGA2.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$76.00
$82.00
$367.00
36
(1)

Glucocorticoids can affect neurodevelopment and may modulate the expression of MDGA2 in the brain.