MAP7D3 activators are a diverse group of chemical compounds that can enhance the expression or activity of the MAP7D3 protein. They can be broadly classified into two main types: direct activators and indirect activators.
Direct activators of MAP7D3 interact directly with the protein and enhance its function. Examples of direct activators include detergents, reducing agents, alkylating agents, and crosslinking agents. Detergents such as SDS, CPC, Triton X-100, octyl glucoside, and digitonin disrupt cell membranes and expose the extracellular domain of MAP7D3 to its ligands. Reducing agents like βME and DTT activate MAP7D3 by breaking disulfide bonds in the protein, exposing cryptic epitopes that can be recognized by antibodies or other ligands. Alkylating agents, such as NEM and IAM, directly activate MAP7D3
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sodium dodecyl sulfate | 151-21-3 | sc-264510 sc-264510A sc-264510B sc-264510C | 25 g 100 g 500 g 1 kg | $78.00 $119.00 $419.00 $603.00 | 11 | |
SDS is an anionic detergent that can activate MAP7D3 by disrupting cell membranes and exposing the extracellular domain of MAP7D3 to its ligands. SDS is a commonly used laboratory detergent that is used to solubilize proteins and disrupt cell membranes. | ||||||
Triton X-100 | 9002-93-1 | sc-29112 sc-29112A | 100 ml 500 ml | $20.00 $42.00 | 55 | |
Triton X-100 is a nonionic detergent that can activate MAP7D3 by disrupting cell membranes and exposing the extracellular domain of MAP7D3 to its ligands. Triton X-100 is a commonly used laboratory detergent that is used to solubilize proteins and disrupt cell membranes. | ||||||
Digitonin | 11024-24-1 | sc-280675A sc-280675 sc-280675B sc-280675C sc-280675D sc-280675E | 100 mg 250 mg 1 g 2.5 g 5 g 10 g | $84.00 $180.00 $385.00 $935.00 $1679.00 $2929.00 | 10 | |
Digitonin is a saponin that can activate MAP7D3 by solubilizing cell membranes and exposing the extracellular domain of MAP7D3 to its ligands. Digitonin is a natural detergent that is often used to solubilize membrane proteins without denaturing them. | ||||||
β-Mercaptoethanol | 60-24-2 | sc-202966A sc-202966 | 100 ml 250 ml | $90.00 $120.00 | 10 | |
βME is a reducing agent that can activate MAP7D3 by breaking disulfide bonds in the protein. This can expose cryptic epitopes on the protein that can be recognized by antibodies or other ligands. βME is a commonly used reducing agent in biochemistry. | ||||||
N-Ethylmaleimide | 128-53-0 | sc-202719A sc-202719 sc-202719B sc-202719C sc-202719D | 1 g 5 g 25 g 100 g 250 g | $22.00 $69.00 $214.00 $796.00 $1918.00 | 19 | |
NEM is an alkylating agent that can activate MAP7D3 by modifying cysteine residues in the protein. This can alter the protein's structure and function. NEM is a commonly used alkylating agent in biochemistry. | ||||||
α-Iodoacetamide | 144-48-9 | sc-203320 | 25 g | $255.00 | 1 | |
IAM is an alkylating agent that can activate MAP7D3 by modifying cysteine residues in the protein. This can alter the protein's structure and function. IAM is a commonly used alkylating agent in biochemistry. | ||||||