MAP7D3 Inhibitors
MAP7D3 inhibitors, in the context provided, primarily target the structural dynamics of microtubules, thereby affecting the interactions and associations of MAP7D3 with these structures. Agents like Vinblastine and Vincristine, found in natural sources, show a proclivity to inhibit tubulin polymerization. By binding to tubulin dimers, these compounds can inhibit the assembly of microtubule structures, indirectly affecting proteins that associate or interact with microtubules, such as MAP7D3.
On the other hand, agents like Taxol and Epothilone B represent a contrasting mechanism. Instead of inhibiting the polymerization, they stabilize the microtubules by binding to them. This stabilization can influence the dynamic functionality of proteins that require the transient assembly and disassembly of microtubules, like MAP7D3. Additionally, compounds like Combretastatin and Colchicine further showcase the diverse ways by which microtubule dynamics can be targeted.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $102.00 $235.00 $459.00 $1749.00 $2958.00 | 4 | |
Binds to tubulin dimers, inhibiting the assembly of microtubule structures, potentially affecting MAP7D3 associations. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Disrupts microtubule polymerization by binding to β-tubulin, impacting potential interactions with MAP7D3. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Stabilizes microtubules by binding to β-tubulin, potentially affecting MAP7D3's dynamic functions. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Binds to tubulin, inhibiting its polymerization into microtubules, possibly affecting MAP7D3's binding. | ||||||
Epothilone B, Synthetic | 152044-54-7 | sc-203944 | 2 mg | $176.00 | ||
Binds to β-tubulin, stabilizing microtubules, which can influence the functionality of associated proteins like MAP7D3. | ||||||
Estramustine | 2998-57-4 | sc-353281 sc-353281A | 100 mg 1 g | $265.00 $743.00 | ||
Combines the actions of a nitrogen mustard and an antimicrotubule agent, potentially affecting MAP7D3 function. | ||||||
Griseofulvin | 126-07-8 | sc-202171A sc-202171 sc-202171B | 5 mg 25 mg 100 mg | $85.00 $220.00 $598.00 | 4 | |
Interacts with polymerized microtubules, potentially affecting MAP7D3's dynamic interactions. | ||||||
Dolastatin 10 | 110417-88-4 | sc-507413 | 5 mg | $980.00 | ||
Inhibits tubulin polymerization, potentially disrupting MAP7D3 interactions with microtubules. | ||||||
Podophyllotoxin | 518-28-5 | sc-204853 | 100 mg | $84.00 | 1 | |
Inhibits microtubule assembly, possibly affecting MAP7D3's binding or functionality. | ||||||
2-Methoxyestradiol | 362-07-2 | sc-201371 sc-201371A | 10 mg 50 mg | $71.00 $288.00 | 6 | |
Inhibits tubulin polymerization, potentially impacting MAP7D3 associations with microtubules. | ||||||