MAO-A Inhibitors
Items 11 to 20 of 24 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Moclobemide | 71320-77-9 | sc-207891 | 10 mg | $91.00 | ||
Moclobemide, as a reversible inhibitor of monoamine oxidase A (MAO-A), showcases unique interactions through its ability to engage in hydrophobic contacts with the enzyme's active site. Its distinct amine group facilitates electrostatic interactions, enhancing binding affinity. The compound's conformational flexibility allows it to adapt to the enzyme's dynamic structure, potentially influencing the rate of substrate turnover and modulating the metabolic pathways of neurotransmitters. | ||||||
Phenethyl-hydrazine | 51-71-8 | sc-331686 | 500 mg | $388.00 | ||
Phenelzine is a non-selective, irreversible MAO inhibitor. It irreversibly binds to MAO-A, inhibiting the degradation of monoamine neurotransmitters like serotonin, norepinephrine, and dopamine. | ||||||
Tetrindole mesylate | 135991-95-6 | sc-204340 sc-204340A | 10 mg 50 mg | $119.00 $446.00 | ||
Tetrindole mesylate acts as a selective inhibitor of monoamine oxidase A (MAO-A), characterized by its unique ability to form hydrogen bonds with specific amino acid residues within the enzyme's active site. This interaction stabilizes the enzyme-inhibitor complex, effectively altering the enzyme's conformation. The compound's lipophilic nature enhances membrane permeability, influencing its distribution and interaction kinetics within biological systems, thereby impacting neurotransmitter metabolism. | ||||||
1-Hydrazinophthalazine Hydrochloride | 304-20-1 | sc-206167 | 10 g | $280.00 | ||
1-Hydrazinophthalazine Hydrochloride exhibits a distinctive mechanism as a monoamine oxidase A (MAO-A) inhibitor, primarily through its capacity to engage in π-π stacking interactions with aromatic residues in the enzyme's active site. This interaction not only modulates the enzyme's activity but also influences the electron density within the active site, potentially affecting substrate binding dynamics. Its hydrophilic characteristics facilitate solubility in aqueous environments, impacting its diffusion and interaction profiles in biological systems. | ||||||
Tranylcypromine | 13492-01-8 | sc-200572 sc-200572A | 1 g 5 g | $172.00 $587.00 | 5 | |
Tranylcypromine is a non-selective, irreversible MAO inhibitor that forms a covalent bond with MAO-A, preventing the breakdown of serotonin, norepinephrine, and dopamine in the synaptic cleft. | ||||||
4-Oxo-4H-1-benzopyran-2-carboxylic acid | 4940-39-0 | sc-238937 | 5 g | $39.00 | ||
4-Oxo-4H-1-benzopyran-2-carboxylic acid acts as a monoamine oxidase A (MAO-A) inhibitor by forming hydrogen bonds with key amino acid residues in the enzyme's active site. This interaction alters the enzyme's conformation, enhancing substrate affinity and modulating reaction kinetics. Its unique structural features, including a fused benzopyran ring, contribute to its stability and reactivity, influencing its overall behavior in biochemical pathways. | ||||||
Furazolidone | 67-45-8 | sc-218546 sc-218546A | 10 g 100 g | $89.00 $260.00 | ||
Furazolidone is a non-selective, irreversible MAO inhibitor. It covalently binds to MAO-A, inhibiting the metabolism of monoamine neurotransmitters. | ||||||
Nialamide | 51-12-7 | sc-253186 | 1 g | $98.00 | ||
Nialamide functions as a monoamine oxidase A (MAO-A) inhibitor through its ability to form covalent interactions with the enzyme's active site, leading to a significant alteration in the enzyme's catalytic efficiency. The presence of a hydrazine moiety enhances its reactivity, allowing for selective binding to the enzyme. This specificity is further influenced by steric factors and electronic distribution within its structure, which modulates the enzyme's activity and impacts metabolic pathways. | ||||||
trans 2-(Phenyl-d5)-cyclopropylamine Hydrochloride | 107077-98-5 | sc-220292 | 1 mg | $290.00 | ||
Trans 2-(Phenyl-d5)-cyclopropylamine Hydrochloride exhibits unique interactions with monoamine oxidase A (MAO-A) through its cyclopropylamine framework, which introduces strain and rigidity to the molecular structure. This configuration enhances its binding affinity, allowing for precise modulation of the enzyme's conformation. The deuterated phenyl group contributes to distinct kinetic properties, influencing reaction rates and selectivity in metabolic processes, while also affecting the stability of enzyme-substrate complexes. | ||||||
Clorgyline hydrochloride | 17780-75-5 | sc-214749 sc-214749A | 50 mg 100 mg | $125.00 $210.00 | 2 | |
Clorgyline hydrochloride is characterized by its selective inhibition of monoamine oxidase A (MAO-A), facilitated by its unique aromatic and aliphatic interactions. The presence of a chlorinated moiety enhances its lipophilicity, promoting effective membrane permeability. This compound's kinetic profile is influenced by its ability to form stable enzyme-inhibitor complexes, which alters the catalytic efficiency of MAO-A, leading to distinct metabolic pathways and regulatory effects on neurotransmitter levels. | ||||||