Molecular structure of Nialamide, CAS Number: 51-12-7
Nialamide (CAS 51-12-7)
Alternate Names:
N-Benzyl-β-(isonicotinylhydrazino)propionamide
CAS Number:
51-12-7
Purity:
≥95%
Molecular Weight:
298.34
Molecular Formula:
C16H18N4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Nialamide is a pyridine-based small molecule non-selective inhibitor of MAO (monoamine oxidase) enzymes. As a non-selective inhibitor, Nialamide is described to inhibit both MAO A and B. Nialamide has been utilized to mediate quinolinic acid-induced hippocampal damage in studies.
Nialamide (CAS 51-12-7) References
- Possible mediation of quinolinic acid-induced hippocampal damage by reactive oxygen species. | Stone, TW., et al. 2000. Amino Acids. 19: 275-81. PMID: 11026499
- Characterization of extracellular dopamine clearance in the medial prefrontal cortex: role of monoamine uptake and monoamine oxidase inhibition. | Wayment, HK., et al. 2001. J Neurosci. 21: 35-44. PMID: 11150317
- The effects of neuroleptics and nialamide on defensive conditoned reflex in rats. | Plech, S., et al. 1975. Acta Physiol Pol. 26: 255-60. PMID: 1180066
- Effect of nialamide and reserpine on brain free amino acids of rat dependent on and withdrawn from morphine. | Koyuncuoglu, H. and Güngör, M. 1975. Arzneimittelforschung. 25: 1762-6. PMID: 1243083
- Potentiation of nialamide-induced hypermotility in mice by lithium and the 5-HT uptake inhibitors chlorimipramine and FG 4963. | Lassen, JB. and Squires, RF. 1976. Neuropharmacology. 15: 665-8. PMID: 137365
- Nialamide-induced hypermotility in mice treated with inhibitors of monoamine uptake, 5-HT antagonists and lithium. | Buus Lassen, J. 1989. Psychopharmacology (Berl). 98: 257-61. PMID: 2526956
- Influence of an inhibitor of monoaminooxidase (nialamide) on the absorption and retention of nitrogen in adult rats. | Barrionuevo, M., et al. 1987. Nahrung. 31: 11-8. PMID: 3614315
- On the role of central nervous system catecholamines and 5-hydroxytryptamine in the nialamide-induced behavioural syndrome. | Modigh, K. and Svensson, TH. 1972. Br J Pharmacol. 46: 32-45. PMID: 4263796
- Effect of nialamide, a monoamine oxidase inhibitor, on acetylcholine-adrenaline induced atrial fibrillation in normal & reserpinized dogs. | Stephen, PM. 1974. Indian J Exp Biol. 12: 499-503. PMID: 4464251
- Double blind trial of nialamide in intermittent claudication. Effects on blood cholesterol, fibrinolysis and 5-hydroxytryptamine. | Tsapogas, MJ. and Flute, PT. 1964. Vasc Dis. 1: 249-51. PMID: 4867905
- Effects of apomorphine, (+)-amphetamine, and nialamide on tetrabenazine-induced suppression of sexual behavior in the male rat. | Butcher, LL., et al. 1969. Eur J Pharmacol. 7: 283-8. PMID: 5351986
- Preventive action of the monoaminooxidase inhibitor, nialamide, on experimental diabetes in rats. | Mordujovich de Buschiazzo, ., et al. 1966. Diabetes. 15: 686-90. PMID: 5920342
- Nialamide-induced potentiation of the anticonvulsant action of phenobarbitone in rat--role of brain monoamines. | Bhattacharya, SK. and Bose, R. 1978. Indian J Med Res. 67: 1045-50. PMID: 721180
Inhibitor of:
MAO-A, and MAO-B.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nialamide, 1 g | sc-253186 | 1 g | $98.00 |