Date published: 2026-5-3

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Macrocycles

Santa Cruz Biotechnology now offers a broad range of macrocycles for use in various applications. Macrocycles, which are large ring molecules consisting of twelve or more atoms, are critical in scientific research due to their unique structural properties and diverse functionalities. These compounds have found extensive use in supramolecular chemistry, where their ability to form host-guest complexes makes them valuable for studying molecular recognition and self-assembly processes. Macrocycles are instrumental in materials science, as their robust frameworks and ability to encapsulate ions or molecules enable the development of advanced materials, such as sensors, catalysts, and nanomaterials. In organic synthesis, macrocycles serve as scaffolds for the construction of complex molecular architectures, facilitating the creation of compounds with specific properties and functions. Environmental chemists utilize macrocycles to develop selective binding agents for pollutant detection and removal, contributing to advancements in environmental remediation technologies. Additionally, macrocycles are crucial in the study of biological systems, where they mimic natural macrocyclic structures like enzymes and nucleic acids, providing insights into biological mechanisms and interactions. Their versatility and capability to undergo functional modifications make macrocycles indispensable tools in research, allowing scientists to explore new chemical spaces and design innovative solutions across various scientific disciplines. View detailed information on our available macrocycles by clicking on the product name.

Items 111 to 120 of 289 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

25-Desacetyl Rifapentin

79039-56-8sc-206559
2.5 mg
$344.00
(0)

25-Desacetyl Rifapentin is a macrocyclic compound distinguished by its intricate ring structure, which facilitates specific molecular interactions through non-covalent forces. This compound exhibits a unique ability to stabilize transient states during chemical reactions, enhancing its kinetic profile. Its conformational flexibility allows for dynamic adjustments in response to environmental changes, while its polar and non-polar regions influence solubility and reactivity in various media.

21-Hydroxyoligomycin A

102042-09-1sc-202013
1 mg
$381.00
(0)

21-Hydroxyoligomycin A is a macrocyclic compound characterized by its unique cyclic architecture, which promotes selective binding interactions with target molecules. This compound exhibits remarkable conformational adaptability, allowing it to engage in diverse reaction pathways. Its ability to form stable complexes with metal ions enhances its reactivity, while the presence of functional groups contributes to its solubility in various solvents, influencing its overall chemical behavior.

1,4,8-Tri-Boc-1,4,8,11-tetraazacyclotetradecane

170161-27-0sc-265082
250 mg
$860.00
(0)

1,4,8-Tri-Boc-1,4,8,11-tetraazacyclotetradecane is a macrocyclic ligand notable for its robust chelating properties, enabling it to form stable complexes with transition metals. The presence of multiple Boc protecting groups enhances its solubility and steric hindrance, facilitating selective interactions in complexation reactions. Its unique cyclic structure allows for distinct conformational flexibility, influencing reaction kinetics and enabling diverse coordination geometries.

Rifamycin B

13929-35-6sc-391444
sc-391444A
50 mg
500 mg
$320.00
$2290.00
(0)

Rifamycin B is a macrocyclic compound characterized by its intricate ring structure, which facilitates unique molecular interactions through non-covalent forces such as hydrogen bonding and π-π stacking. This configuration allows for selective binding to specific targets, influencing reaction kinetics and enhancing stability in various environments. Its hydrophobic regions contribute to solubility dynamics, while the cyclic nature promotes conformational adaptability, impacting its reactivity and interaction pathways.

Davercin

55224-05-0sc-391506
1 mg
$150.00
(0)

Davercin is a macrocyclic compound distinguished by its large, flexible ring system, which enables it to engage in diverse molecular interactions, including metal coordination and hydrophobic effects. This structural complexity allows for unique conformational changes that can influence reaction pathways and kinetics. Its ability to form stable complexes with various substrates enhances its reactivity, while the presence of polar and non-polar regions affects solubility and distribution in different media.

Pd(II) meso-Tetra(pentafluorophenyl)porphine

72076-09-6sc-263974
sc-263974A
100 mg
1 g
$234.00
$826.00
(0)

Pd(II) meso-Tetra(pentafluorophenyl)porphine is a macrocyclic compound characterized by its robust porphyrin framework, which facilitates strong π-π stacking interactions and metal coordination. The presence of pentafluorophenyl groups enhances electron-withdrawing properties, influencing redox behavior and catalytic activity. Its unique geometry allows for selective binding with substrates, promoting distinct reaction pathways and altering kinetic profiles, while its hydrophobic character affects solubility in organic solvents.

Bis(Zinc Porphyrin) (c)

92995-45-4sc-293524
sc-293524A
5 ml
25 ml
$90.00
$273.00
(0)

Bis(zinc porphyrin) is a macrocyclic compound notable for its dual zinc coordination, which stabilizes the porphyrin structure and enhances its electronic properties. The compound exhibits significant intermolecular interactions, including hydrogen bonding and π-π stacking, which influence its aggregation behavior. Its unique planar geometry facilitates efficient energy transfer processes, while the metal centers modulate reactivity, allowing for tailored catalytic pathways in various chemical environments.

1,4,7-Trimethyl-1,4,7-triazacyclononane

96556-05-7sc-253994
100 mg
$62.00
(0)

1,4,7-Trimethyl-1,4,7-triazacyclononane is a macrocyclic ligand characterized by its ability to form stable complexes with transition metals. The cyclic structure promotes unique chelation properties, enhancing metal ion selectivity and coordination geometry. Its nitrogen-rich framework facilitates strong electrostatic interactions, influencing solubility and reactivity. The compound's conformational flexibility allows for dynamic binding modes, which can significantly affect reaction kinetics and catalytic efficiency in diverse chemical systems.

Araguspongin B

123000-02-2sc-205215
sc-205215A
100 µg
250 µg
$490.00
$1170.00
1
(0)

Araguspongin B is a macrocyclic compound distinguished by its intricate ring structure, which fosters unique intramolecular interactions. This configuration enhances its ability to engage in host-guest chemistry, allowing for selective encapsulation of smaller molecules. The compound exhibits notable conformational adaptability, influencing its reactivity and interaction with various substrates. Its hydrophobic regions contribute to solubility variations, impacting its behavior in different environments.

Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetate Hydrobromide

149353-23-1sc-391407
100 mg
$360.00
(0)

Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetate Hydrobromide is a macrocyclic ligand characterized by its robust framework and multiple coordination sites. This structure facilitates strong metal ion complexation, leading to distinct electronic properties and enhanced stability. The compound's steric bulk promotes selective interactions, influencing reaction kinetics and pathways. Its solubility profile varies with pH, affecting its behavior in diverse chemical environments.