LYPLA3 Activators
LYPLA3 activators belong to a specific chemical class of compounds that are designed to modulate the activity of lysophospholipase 3 (LYPLA3), an enzyme involved in lipid metabolism. These activators are a part of the broader field of enzymology and chemical biology, where researchers aim to understand and manipulate the functions of enzymes for various purposes. LYPLA3 is a phospholipase enzyme that plays a pivotal role in lipid metabolism by catalyzing the hydrolysis of lysophosphatidylcholine (LPC) molecules. LPCs are a type of phospholipid found in cell membranes and lipoproteins, and their breakdown by LYPLA3 is essential for maintaining lipid homeostasis within cells.
The specific chemical structures and mechanisms of action of LYPLA3 activators can vary widely, as researchers have developed various small molecules and compounds to target this enzyme. These activators typically work by enhancing the catalytic activity of LYPLA3, thereby increasing its ability to cleave LPC molecules. This modulation of LYPLA3 activity can have a profound impact on cellular lipid metabolism and signaling pathways. Studying LYPLA3 activators is crucial for understanding the intricate regulation of lipid metabolism and its implications for cellular function.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Arachidonic Acid (20:4, n-6) | 506-32-1 | sc-200770 sc-200770A sc-200770B | 100 mg 1 g 25 g | $92.00 $240.00 $4328.00 | 9 | |
Directly activates LYPLA3 as a substrate, initiating enzyme activation through hydrolysis. | ||||||
Oleic Acid | 112-80-1 | sc-200797C sc-200797 sc-200797A sc-200797B | 1 g 10 g 100 g 250 g | $37.00 $104.00 $580.00 $1196.00 | 10 | |
Functions as a direct substrate for LYPLA3, initiating enzyme activation via lipid hydrolysis. | ||||||
Linoleic Acid | 60-33-3 | sc-200788 sc-200788A sc-200788B sc-200788C | 100 mg 1 g 5 g 25 g | $34.00 $64.00 $166.00 $281.00 | 4 | |
Directly activates LYPLA3 as it is hydrolyzed from phospholipids, initiating the enzyme's activity. | ||||||
Calcium | 7440-70-2 | sc-252536 | 5 g | $209.00 | ||
Indirectly influences LYPLA3 by binding to the enzyme and modulating its conformation, leading to activation. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Indirectly activates LYPLA3 by initiating PKC activation, which subsequently activates LYPLA3. | ||||||
Triton X-100 | 9002-93-1 | sc-29112 sc-29112A | 100 ml 500 ml | $20.00 $42.00 | 55 | |
Indirectly activates LYPLA3 by solubilizing cell membranes, making lipid substrates more accessible for hydrolysis. | ||||||