Ly-55A Activators primarily enhance specific signaling pathways, such as the Wnt and Hedgehog pathways, in which Ly-55A is directly involved. Lithocholic acid, Alprostadil, Oleoylethanolamide, SAG, Purmorphamine, Forskolin, Rolipram, Sildenafil, Picrotoxin, Nicotine, Anandamide, and Capsaicin can influence these pathways, leading to the enhancement of Ly-55A functional activity. These compounds act on specific pathways or biological processes directly involved in Ly-55A function, leading to its enhanced activity.
Lithocholic acid, Alprostadil, Forskolin, Rolipram, and Sildenafil enhance the intracellular levels of cAMP, an important second messenger in many cellular processes. They increase intracellular cAMP levels by activating adenylate cyclase or inhibiting phosphodiesterase. This leads to the activation of the Wnt signaling pathway, which can enhance the functional activity of Ly-55A. On the other hand, Oleoylethanolamide, SAG, Purmorphamine, Picrotoxin, Nicotine, Anandamide, and Capsaicin influence the activation of Wnt or Hedgehog signaling by acting on specific receptors or pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lithocholic acid | 434-13-9 | sc-215262 sc-215262A | 10 g 25 g | $100.00 $272.00 | 1 | |
Lithocholic acid activates the TGR5 receptor, leading to a rise in cAMP levels, which can activate the Wnt signaling pathway. Ly-55A operates within this pathway, and its functional activity is enhanced when the pathway is activated by this bile acid. | ||||||
PGE1 (Prostaglandin E1) | 745-65-3 | sc-201223 sc-201223A | 1 mg 10 mg | $31.00 $145.00 | 16 | |
Alprostadil is a prostaglandin E1 analog that stimulates adenylate cyclase, increasing cAMP levels. The rise in cAMP levels activates the Wnt signaling pathway, enhancing the functional activity of Ly-55A, a protein operating within this pathway. | ||||||
Oleylethanolamide | 111-58-0 | sc-201400 sc-201400A | 10 mg 50 mg | $90.00 $194.00 | 1 | |
This PPAR-alpha agonist, Oleoylethanolamide, upregulates the Wnt signaling pathway. As Ly-55A functions within this pathway, its activity is enhanced when the pathway is activated by this compound. | ||||||
Smoothened Agonist, HCl | 364590-63-6 | sc-202814 sc-202814A | 1 mg 5 mg | $210.00 $520.00 | 31 | |
SAG, a Smoothened agonist, activates the Hedgehog signaling pathway. This pathway's activation indirectly leads to the activation of the Wnt signaling pathway, in which Ly-55A operates, enhancing its functional activity. | ||||||
Purmorphamine | 483367-10-8 | sc-202785 sc-202785A | 1 mg 5 mg | $57.00 $184.00 | 18 | |
Purmorphamine activates the Hedgehog signaling pathway, which subsequently leads to the activation of the Wnt signaling pathway. This activation enhances the functional activity of Ly-55A, a protein that functions within this pathway. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin, an adenylate cyclase activator, elevates cAMP levels. The increased cAMP levels activate the Wnt signaling pathway, enhancing the functional activity of Ly-55A, a protein involved in this pathway. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram inhibits phosphodiesterase, leading to increased cAMP levels. The elevated cAMP levels activate the Wnt signaling pathway, enhancing the functional activity of Ly-55A, a protein that operates within this pathway. | ||||||
Picrotoxin | 124-87-8 | sc-202765 sc-202765A sc-202765B | 1 g 5 g 25 g | $67.00 $286.00 $1326.00 | 11 | |
Picrotoxin antagonizes the GABA-A receptor, indirectly leading to the activation of the Wnt signaling pathway. Ly-55A, a protein that functions within this pathway, has its activity enhanced when the pathway is activated by this compound. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin activates the TRPV1 receptor, indirectly leading to the activation of the Wnt signaling pathway. Ly-55A, a protein that functions within this pathway, has its functional activity enhanced when the pathway is activated by this compound. | ||||||