LRRC26 inhibitors belong to a distinct chemical class that specifically targets Leucine-rich repeat-containing protein 26 (LRRC26). LRRC26 is a member of the leucine-rich repeat (LRR) protein family, characterized by the presence of LRR motifs, which are involved in protein-protein interactions. LRRC26 itself plays a crucial role in various cellular processes, acting as a scaffolding protein that participates in the formation of multiprotein complexes. These complexes are implicated in signal transduction pathways, molecular recognition, and the regulation of diverse cellular functions.
LRRC26 function typically possess a specific chemical structure that allows them to interact with the target protein, disrupting its normal physiological interactions. This disruption may result in altered cellular signaling cascades or hinder the assembly of protein complexes, thereby influencing downstream cellular responses. The development of LRRC26 inhibitors involves a comprehensive understanding of the protein's structure and function, enabling the design of molecules with high specificity and affinity for the target. Researchers in this field employ various techniques, including computational modeling, structural biology, and medicinal chemistry, to optimize the chemical properties of LRRC26 inhibitors for enhanced potency and selectivity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Iberiotoxin | 129203-60-7 | sc-3585 sc-3585A | 10 µg 100 µg | $270.00 $490.00 | 16 | |
Iberiotoxin is a peptide toxin that specifically blocks BK channels, which could indirectly affect the modulation by LRRC26. | ||||||
Charybdotoxin | 95751-30-7 | sc-200979 | 100 µg | $401.00 | 9 | |
Charybdotoxin is a toxin that blocks potassium channels including BK channels, likely altering the modulation effect of LRRC26 on these channels. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc Pyrithione is known to block potassium channels among other targets, possibly impacting LRRC26-associated modulation. | ||||||
Clofilium tosylate | 92953-10-1 | sc-391228 sc-391228A | 25 mg 100 mg | $428.00 $1020.00 | 1 | |
Clofilium Tosylate is a potassium channel blocker that might indirectly influence LRRC26's regulatory effect on BK channels. | ||||||
Lanthanum(III) chloride | 10099-58-8 | sc-257661 | 10 g | $88.00 | ||
Lanthanum(III) chloride can inhibit various types of potassium channels, likely changing LRRC26's action on BK channel modulation. | ||||||