LRP5L Activators
LRP5L Activators function primarily by enhancing specific signaling pathways, such as the Wnt and Hedgehog pathways, in which LRP5L is directly involved. Lithocholic acid, Alprostadil, Oleoylethanolamide, SAG, Purmorphamine, Forskolin, Rolipram, Sildenafil, Picrotoxin, Nicotine, Anandamide, and Capsaicin can influence these pathways, leading to the enhancement of LRP5L function. These compounds act on specific pathways or biological processes directly involved in LRP5L function, leading to its enhanced activity.
Lithocholic acid, Alprostadil, Forskolin, Rolipram, and Sildenafil enhance the intracellular levels of cyclic adenosine monophosphate (cAMP), a pivotal second messenger in many cellular processes. They increase intracellular cAMP levels by activating adenylate cyclase or inhibiting phosphodiesterase. This leads to the activation of Wnt signaling, which can enhance the functional activity of LRP5L. On the other hand, Oleoylethanolamide, SAG, Purmorphamine, Picrotoxin, Nicotine, Anandamide, and Capsaicin influence the activation of Wnt or Hedgehog signaling by acting on specific receptors or pathways.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lithocholic acid | 434-13-9 | sc-215262 sc-215262A | 10 g 25 g | $100.00 $272.00 | 1 | |
Lithocholic acid is a bile acid that can activate the TGR5 receptor. This activation leads to a rise in cAMP levels, which could indirectly activate LRP5L through the activation of Wnt signaling, a pathway in which LRP5L is involved. | ||||||
PGE1 (Prostaglandin E1) | 745-65-3 | sc-201223 sc-201223A | 1 mg 10 mg | $31.00 $145.00 | 16 | |
Alprostadil is a prostaglandin E1 analog that can stimulate adenylate cyclase, leading to increased cAMP levels. The elevated cAMP levels can activate Wnt signaling, thereby potentially enhancing the functional activity of LRP5L. | ||||||
Oleylethanolamide | 111-58-0 | sc-201400 sc-201400A | 10 mg 50 mg | $90.00 $194.00 | 1 | |
Oleoylethanolamide is a PPAR-alpha agonist. Its activation of PPAR-alpha can lead to the upregulation of Wnt signaling, thereby potentially enhancing the function of LRP5L. | ||||||
Smoothened Agonist, HCl | 364590-63-6 | sc-202814 sc-202814A | 1 mg 5 mg | $210.00 $520.00 | 31 | |
SAG is a Smoothened agonist that can activate the Hedgehog signaling pathway. This activation can indirectly lead to the activation of Wnt signaling, thereby potentially enhancing the function of LRP5L. | ||||||
Purmorphamine | 483367-10-8 | sc-202785 sc-202785A | 1 mg 5 mg | $57.00 $184.00 | 18 | |
Purmorphamine activates the Hedgehog signaling pathway, which can indirectly lead to the activation of Wnt signaling. This potential enhancement of Wnt signaling could indirectly enhance the function of LRP5L. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is an adenylate cyclase activator that elevates cAMP levels. The increased cAMP can activate Wnt signaling, potentially enhancing the function of LRP5L. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram inhibits phosphodiesterase, leading to increased cAMP levels. The elevated cAMP levels can activate Wnt signaling, leading to a potential enhancement in the function of LRP5L. | ||||||
Picrotoxin | 124-87-8 | sc-202765 sc-202765A sc-202765B | 1 g 5 g 25 g | $67.00 $286.00 $1326.00 | 11 | |
Picrotoxin is a GABA-A receptor antagonist. By antagonizing this receptor, it can indirectly lead to the activation of Wnt signaling, potentially enhancing the function of LRP5L. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin activates the TRPV1 receptor. This activation can indirectly lead to the activation of Wnt signaling, potentially enhancing the function of LRP5L. | ||||||