LOC729460 Inhibitors
LY294002 and Wortmannin are both inhibitors of PI3K, which is pivotal in the PI3K/AKT pathway, a critical regulator of cellular functions such as growth, metabolism, and survival. The inhibition of this pathway can lead to reduced activity of downstream effectors, possibly impacting LOC729460 if it is a downstream target. Rapamycin specifically inhibits mTOR, a central component in cell growth and proliferation, and its inhibition can have far-reaching effects on cellular processes.
PD98059 and U0126 both target MEK, a key enzyme in the MAPK/ERK pathway, which plays a critical role in cell division and differentiation. SP600125 and SB203580 inhibit JNK and p38 MAPK, respectively, both of which are involved in cellular responses to stress and inflammation. These inhibitors can modify the cellular environment, potentially affecting the stability or activity of LOC729460. PP2 and Ibrutinib target kinases involved in cell signaling related to growth, differentiation, and survival. ZM-447439 disrupts cell cycle progression by inhibiting Aurora kinases, which are essential for mitotic spindle assembly. BML-275 targets AMPK, a regulator of energy homeostasis, and Thapsigargin disrupts calcium homeostasis by inhibiting the SERCA pump, potentially affecting numerous calcium-dependent processes.
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor that can prevent the activation of AKT, affecting cell survival and growth signals. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
mTOR inhibitor that can suppress cell growth and proliferation pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Another PI3K inhibitor that can block the PI3K/AKT pathway, influencing metabolic and survival responses. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
MEK inhibitor that can prevent the activation of the MAPK/ERK pathway, affecting cell division and differentiation. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor that can modulate stress response pathways and inflammation. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
p38 MAPK inhibitor that can alter inflammatory cytokine production and stress responses. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
MEK inhibitor that can also prevent the activation of the MAPK/ERK pathway. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
Src family kinase inhibitor that can affect cell adhesion, growth, and differentiation. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $153.00 $356.00 | 15 | |
Aurora kinase inhibitor that can disrupt spindle assembly and cell cycle progression. | ||||||
BML-275 | 866405-64-3 | sc-200689 sc-200689A | 5 mg 25 mg | $96.00 $355.00 | 69 | |
AMPK inhibitor that can impact energy homeostasis and metabolic signaling. | ||||||