LOC645553 Inhibitors
The term LOC645553 Inhibitors characterizes a specialized class of chemical compounds meticulously designed to modulate the activity of LOC645553, a molecular target currently under scientific investigation. These inhibitors are crafted through principles rooted in medicinal chemistry, with a primary focus on selectively interfering with the normal functions of LOC645553 within cellular processes. The structural features of LOC645553 Inhibitors undergo a meticulous optimization process, often involving computational modeling and structure-activity relationship studies, to refine their molecular configurations for precise binding to the target.
The significance of LOC645553 Inhibitors lies in their potential to disrupt the biochemical activities associated with LOC645553, a molecular entity believed to play a role in various biological pathways. Researchers in this field delve into the three-dimensional structure of LOC645553 and its binding interactions with inhibitors, aiming to unravel the intricate molecular mechanisms underlying inhibition. The study of LOC645553 Inhibitors contributes to a broader understanding of cellular processes, offering insights into the roles played by LOC645553 in diverse biological pathways and expanding our knowledge of the regulatory networks governing cellular activities. This research not only advances our comprehension of the molecular intricacies surrounding LOC645553 but also contributes to the broader scientific understanding of molecular targets and their involvement in fundamental cellular functions.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
α-Amanitin is a potent inhibitor of RNA polymerase II, the enzyme responsible for transcribing mRNA, which could also affect the transcription of antisense RNAs. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
This compound is known to inhibit bacterial RNA polymerase, and while it's less effective in eukaryotes, it may still decrease RNA synthesis non-specifically. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D intercalates into DNA, inhibiting RNA polymerase movement and blocking both mRNA and non-coding RNA synthesis. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
Cordycepin (3'-deoxyadenosine) leads to the premature termination of RNA chain elongation, affecting RNA synthesis. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
DRB is an adenosine analog that inhibits RNA synthesis by targeting RNA polymerase II. | ||||||
Leptomycin B | 87081-35-4 | sc-358688 sc-358688A sc-358688B | 50 µg 500 µg 2.5 mg | $105.00 $408.00 $1224.00 | 35 | |
Leptomycin B inhibits the export of RNA from the nucleus to the cytoplasm, which could reduce RNA levels indirectly. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide has been shown to inhibit the transcription of various RNAs by affecting RNA polymerase II activity. | ||||||
β-Lapachone | 4707-32-8 | sc-200875 sc-200875A | 5 mg 25 mg | $110.00 $450.00 | 8 | |
β-Lapachone has been reported to cause the degradation of RNA polymerase II, thereby decreasing RNA synthesis. | ||||||
Flavopiridol Hydrochloride | 131740-09-5 | sc-207687 | 10 mg | $311.00 | ||
Flavopiridol inhibits cyclin-dependent kinases, which are necessary for RNA polymerase II-mediated transcription. | ||||||