LOC100041442 Inhibitors
LOC100041442 may be inhibited by compounds like Cyclosporin A and 2-Deoxy-D-glucose provide examples of inhibitors that affect T-cell activation and cellular metabolism, respectively. The influence on these pathways can lead to altered cellular states that indirectly modulate proteins like LOC100041442. Alsterpaullone and Chelerythrine, which inhibit cyclin-dependent kinases and protein kinase C, showcase the impact on cell cycle control and signal transduction pathways that can have cascading effects on protein regulation. PD98059 and LY294002 are more examples, targeting key kinases within the MAPK/PI3K pathways, with downstream effects that may extend to LOC100041442.
Other inhibitors such as SP600125 and Y-27632 target stress response pathways and cytoskeletal dynamics, respectively. These pathways can have profound effects on the cellular environment, influencing the behavior and interaction of proteins. Okadaic acid, a potent inhibitor of protein phosphatases, can shift the phosphorylation equilibrium, leading to changes in protein activity and interaction networks. Thapsigargin disrupts calcium signaling, a universal second messenger affecting a multitude of cellular processes, which can indirectly modulate the function of proteins like LOC100041442.
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent kinase inhibitor, can inhibit a wide range of protein kinases, potentially affecting kinase-dependent regulation of LOC100041442. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibits mTOR signaling, which can lead to altered protein synthesis and affect proteins involved in this pathway, possibly including LOC100041442. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
An immunosuppressant that inhibits calcineurin, can alter T-cell activation pathways and may indirectly affect proteins associated with this pathway. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
A glycolysis inhibitor, can reduce energy production, indirectly affecting proteins that are energy-dependent. | ||||||
Alsterpaullone | 237430-03-4 | sc-202453 sc-202453A | 1 mg 5 mg | $67.00 $306.00 | 2 | |
A cyclin-dependent kinase inhibitor, can halt cell cycle progression and may impact proteins that are regulated during the cell cycle. | ||||||
Chelerythrine chloride | 3895-92-9 | sc-3547 sc-3547A | 5 mg 25 mg | $88.00 $311.00 | 17 | |
A potent inhibitor of protein kinase C, can affect signaling pathways that are mediated by PKC, thereby potentially influencing LOC100041442 activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Specifically inhibits MEK1/2 in the MAPK pathway, can affect proteins downstream in this pathway. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor, can prevent the phosphorylation and activation of proteins within the PI3K/Akt pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK, can influence stress response signaling and proteins involved in this pathway. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
A selective inhibitor of ROCK kinases, can affect cytoskeleton organization and cell adhesion dynamics. | ||||||