LL-37 Inhibitors
Common LL-37 Inhibitors include, but are not limited to 5-Methylcytosine CAS 554-01-8, Glycyrrhizic acid CAS 1405-86-3, Lactoferrin, Polymyxin B1 Sulfate CAS 4135-11-9 and 5-Methylcytosine CAS 554-01-8.
LL-37 inhibitors belong to a distinctive category of compounds meticulously designed to target and modulate the activity of LL-37, a cationic antimicrobial peptide. LL-37 is a key component of the innate immune system and plays a crucial role in the body's defense against microbial infections. It is known for its antimicrobial properties, as well as its ability to modulate immune responses, regulate inflammation, and contribute to wound healing.
The inhibitors tailored for LL-37 aim to interfere with its biological functions, including its antimicrobial and immune-modulatory activities. By interacting with specific sites on LL-37, these inhibitors hold the ability to influence its ability to bind to microbial membranes, disrupt their integrity, and neutralize their growth. Additionally, LL-37 inhibitors offer an avenue to investigate the intricate molecular mechanisms underlying the peptide's role in immunity and inflammation. Through the exploration of LL-37 inhibitors, researchers gain insights into the complex interplay between host defense mechanisms and microbial pathogens, shedding light on the dynamic interactions that shape the immune responses of the body.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Methylcytosine | 554-01-8 | sc-278268 sc-278268A sc-278268B | 100 mg 500 mg 1 g | $300.00 $600.00 $1200.00 | ||
5-Methylcytosine is a small molecule that might inhibit LL-37 activity by interfering with its interaction with bacterial DNA, affecting antimicrobial properties. | ||||||
Glycyrrhizic acid | 1405-86-3 | sc-279186 sc-279186A | 1 g 25 g | $56.00 $326.00 | 7 | |
Glycyrrhizin is a natural compound that might inhibit LL-37-mediated immune responses by modulating the expression of inflammatory cytokines and chemokines. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
N-Acetyl-L-cysteine (NAC) might inhibit LL-37 activity by modulating oxidative stress and cytokine production, potentially impacting the peptide's immunomodulatory functions. | ||||||
Lactoferrin | 146897-68-9 | sc-394420 sc-394420A sc-394420B sc-394420C | 10 mg 50 mg 100 mg 1 g | $120.00 $400.00 $569.00 $1465.00 | ||
Lactoferrin might interact with LL-37, potentially affecting its antimicrobial activity by modulating its interactions with microbial membranes. | ||||||
Polymyxin B Sulfate | 1405-20-5 | sc-3544 | 500 mg | $62.00 | 8 | |
Polymyxins might interfere with LL-37 interactions with bacterial membranes, potentially affecting its antimicrobial activity and membrane disruption. | ||||||