Date published: 2026-6-22

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LIN-41 Inhibitors

LIN-41 inhibitors belong to a class of chemical compounds developed to target and inhibit the activity of LIN-41, a conserved protein involved in the regulation of gene expression and post-transcriptional processes. LIN-41 is part of the LIN-4 microRNA pathway, which plays a crucial role in controlling developmental timing and cell fate determination in various organisms, including Caenorhabditis elegans, a model organism for genetic studies. LIN-41 is responsible for binding to specific messenger RNAs (mRNAs) and influencing their stability and translation, thus affecting the levels of target proteins. Inhibitors of LIN-41 are essential tools for researchers studying gene regulation, developmental biology, and post-transcriptional control mechanisms.

Typically composed of small molecules or chemical compounds, LIN-41 inhibitors are designed to interfere with the activity or interactions of LIN-41 within cellular pathways. By inhibiting LIN-41, these compounds can potentially disrupt its regulatory functions, leading to changes in the expression of target genes and the proteins they encode. Researchers use LIN-41 inhibitors in laboratory settings to modulate LIN-41-mediated post-transcriptional processes and investigate their roles in various biological contexts. These inhibitors provide valuable insights into the molecular mechanisms by which LIN-41 contributes to gene regulation and developmental processes, enhancing our understanding of the complex interplay between microRNAs, mRNA stability, and protein expression. While LIN-41 inhibitors may have broader implications, their primary purpose is to assist scientists in deciphering the intricate roles of LIN-41 in post-transcriptional control.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

This agent can cause DNA demethylation, possibly affecting gene expression patterns including the silencing of genes like LIN-41.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

Histone deacetylase inhibitor that can change chromatin structure, potentially decreasing LIN-41 expression by altering gene accessibility.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

A histone deacetylase inhibitor that may lead to a more relaxed chromatin structure, potentially downregulating LIN-41 expression.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Affects gene expression through retinoic acid receptors; it may impact LIN-41 expression as part of the regulation of differentiation processes.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

An mTOR inhibitor that can suppress protein synthesis, potentially affecting the translation of mRNAs such as that of LIN-41.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

By binding to DNA, it inhibits RNA polymerase and can suppress gene transcription broadly, potentially including LIN-41.

Mithramycin A

18378-89-7sc-200909
1 mg
$55.00
6
(1)

A DNA-binding compound that can inhibit transcription factor binding, possibly affecting LIN-41 gene expression.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$41.00
$84.00
$275.00
127
(6)

Inhibits eukaryotic protein synthesis, possibly leading to a generalized decrease in protein levels, including LIN-41.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$269.00
$1050.00
26
(2)

Specifically inhibits RNA polymerase II, which could reduce transcription of protein-coding genes like LIN-41.

Chloroquine

54-05-7sc-507304
250 mg
$69.00
2
(0)

Known to alter DNA and RNA synthesis by intercalating into nucleic acids, potentially affecting LIN-41 gene expression.