LEPROT Inhibitors
LEPROT inhibitors belong to a distinct chemical class of compounds that specifically target the LEPROT (Leptin Receptor Overlapping Transcript) protein. LEPROT is a relatively recently discovered protein with functions that are still being elucidated by researchers. These inhibitors are designed to modulate the activity of LEPROT through their unique chemical structure, allowing for the investigation of the protein's role in various physiological processes. LEPROT itself is involved in complex cellular pathways related to metabolism and energy regulation, and its inhibitors provide valuable tools for scientists to better understand these intricate mechanisms.
LEPROT inhibitors represents a significant advancement in molecular biology and as they enable researchers to explore the precise functions of LEPROT in cellular homeostasis, signaling cascades, and potential interactions with other proteins. By inhibiting LEPROT activity, these compounds can offer insights into how the protein influences cellular processes such as lipid metabolism, insulin signaling, and possibly even appetite regulation. This chemical class serves as a valuable resource for scientists aiming to unravel the intricacies of LEPROT's role in health and disease.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Tyrphostin B42 | 133550-30-8 | sc-3556 | 5 mg | $26.00 | 4 | |
JAK2 inhibitor, may indirectly inhibit LEPROT by preventing phosphorylation events downstream of leptin receptor signaling, which could affect LEPROT's function in vesicle sorting and leptin signaling modulation. | ||||||
Stat3 Inhibitor III, WP1066 | 857064-38-1 | sc-203282 | 10 mg | $132.00 | 72 | |
Blocks JAK2/STAT3 signaling; could disrupt leptin signaling, potentially affecting LEPROT's role in this pathway by altering the endocytosis and recycling of leptin receptors, which might affect leptin sensitivity. | ||||||
Stat3 Inhibitor VI, S3I-201 | 501919-59-1 | sc-204304 | 10 mg | $148.00 | 104 | |
STAT3 inhibitor, may alter the transcriptional outcomes of leptin signaling, indirectly influencing LEPROT's modulation of the leptin receptor's cellular trafficking. | ||||||
Piceatannol | 10083-24-6 | sc-200610 sc-200610A sc-200610B | 1 mg 5 mg 25 mg | $50.00 $70.00 $195.00 | 11 | |
Inhibits Syk kinase; by doing so, it possibly alters the leptin receptor signaling complex, which can have downstream effects on LEPROT functionality in leptin receptor trafficking and signaling. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
Src family kinase inhibitor, potentially alters leptin receptor signaling complexes, which might influence LEPROT's role in leptin receptor trafficking. | ||||||
Erlotinib, Free Base | 183321-74-6 | sc-396113 sc-396113A sc-396113B sc-396113C sc-396113D | 500 mg 1 g 5 g 10 g 100 g | $85.00 $132.00 $287.00 $495.00 $3752.00 | 42 | |
EGFR inhibitor, indirectly influences leptin receptor pathway by modulation of cross-talk between EGFR and leptin receptor signaling, which might affect the function of LEPROT. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
RAF inhibitor, may impact leptin signaling pathway indirectly, possibly affecting LEPROT's function in the modulation of leptin receptor signaling. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
Src family kinase inhibitor, could affect leptin receptor signaling pathway, thus potentially influencing the LEPROT's role in the trafficking and function of the leptin receptor. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
MEK inhibitor, by inhibiting MEK, it may indirectly affect the leptin receptor signaling pathway, which could influence LEPROT's role in leptin receptor trafficking and signaling. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor, potentially affects leptin signaling by altering the AKT pathway, which may influence LEPROT's function in leptin receptor trafficking and signaling modulation. | ||||||