Date published: 2025-11-21

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Lefty Antibodies

Santa Cruz Biotechnology features a diverse variety of Lefty Antibodies for advanced research in developmental biology and stem cell differentiation. Lefty Antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Lefty proteins regulate embryonic development and maintain pluripotency in stem cells through inhibition of the Nodal signaling pathway. Understanding Lefty's role in development has significant implications for identifying potential therapeutic strategies in regenerative medicine. Researchers worldwide utilize Lefty monoclonal antibodies to investigate cellular signaling mechanisms during embryogenesis. The molecular interactions between Lefty and the Nodal pathway reveal essential insights about early developmental processes and stem cell maintenance. Current studies focusing on Lefty continue to uncover new aspects of embryonic patterning and tissue formation. Santa Cruz Biotechnology monoclonal antibodies for Lefty research support scientists in advancing our understanding of developmental biology and regenerative medicine applications.

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Lefty Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Lefty Antibody (D-6)

sc-365845mouse IgG1 κ327-352 (m)WB, IP, IF, ELISAm, r, h
2
(4)

Lefty Antibody (F-11)

sc-166708mouse IgG2b κ77-366 (h)WB, IP, IF, ELISAm, r, h
1
(2)

Lefty CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Lefty-A CRISPR/Cas9 KO Plasmid (h)

sc-403932hGene KnockoutGFP0
(0)

Lefty-A HDR Plasmid (h)

sc-403932-HDRhHomology Directed RepairPuromycin0
(0)

Lefty-A Double Nickase Plasmid (h)

sc-403932-NIChGene KnockoutPuromycin0
(0)

Lefty-A Double Nickase Plasmid (h2)

sc-403932-NIC-2hGene KnockoutPuromycin0
(0)

Lefty-B CRISPR/Cas9 KO Plasmid (h)

sc-411497hGene KnockoutGFP0
(0)

Lefty-B HDR Plasmid (h)

sc-411497-HDRhHomology Directed RepairPuromycin0
(0)

Lefty-B Double Nickase Plasmid (h)

sc-411497-NIChGene KnockoutPuromycin0
(0)

Lefty-B Double Nickase Plasmid (h2)

sc-411497-NIC-2hGene KnockoutPuromycin0
(0)

Lefty-1 CRISPR/Cas9 KO Plasmid (m)

sc-420092mGene KnockoutGFP0
(0)

Lefty-1 HDR Plasmid (m)

sc-420092-HDRmHomology Directed RepairPuromycin0
(0)

Lefty-1 Double Nickase Plasmid (m)

sc-420092-NICmGene KnockoutPuromycin0
(0)

Lefty-1 Double Nickase Plasmid (m2)

sc-420092-NIC-2mGene KnockoutPuromycin0
(0)

Lefty-2 CRISPR/Cas9 KO Plasmid (m)

sc-435732mGene KnockoutGFP0
(0)

Lefty-2 HDR Plasmid (m)

sc-435732-HDRmHomology Directed RepairPuromycin0
(0)

Lefty-2 Double Nickase Plasmid (m)

sc-435732-NICmGene KnockoutPuromycin0
(0)

Lefty-2 Double Nickase Plasmid (m2)

sc-435732-NIC-2mGene KnockoutPuromycin0
(0)

Lefty CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Lefty CRISPR Activation Plasmid (h)

sc-411497-ACThGene ActivationPuro, Blast, Hygro0
(0)

Lefty-A CRISPR Activation Plasmid (h)

sc-403932-ACThGene ActivationPuro, Blast, Hygro0
(0)

Lefty-A CRISPR Activation Plasmid (h2)

sc-403932-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Lefty-A Lentiviral Activation Particles (h)

sc-403932-LAChGene ActivationPuro, Blast, Hygro0
(0)

Lefty-A Lentiviral Activation Particles (h2)

sc-403932-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Lefty-B CRISPR Activation Plasmid (h2)

sc-411497-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Lefty-B Lentiviral Activation Particles (h)

sc-411497-LAChGene ActivationPuro, Blast, Hygro0
(0)

Lefty-B Lentiviral Activation Particles (h2)

sc-411497-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Lefty-1 CRISPR Activation Plasmid (m)

sc-420092-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Lefty-1 CRISPR Activation Plasmid (m2)

sc-420092-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Lefty-1 Lentiviral Activation Particles (m)

sc-420092-LACmGene ActivationPuro, Blast, Hygro0
(0)

Lefty-1 Lentiviral Activation Particles (m2)

sc-420092-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Lefty-2 CRISPR Activation Plasmid (m)

sc-435732-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Lefty-2 CRISPR Activation Plasmid (m2)

sc-435732-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Lefty-2 Lentiviral Activation Particles (m)

sc-435732-LACmGene ActivationPuro, Blast, Hygro0
(0)

Lefty-2 Lentiviral Activation Particles (m2)

sc-435732-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Lefty siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Lefty siRNA (h)

sc-43894hGene SilencingN/A0
(0)

Lefty shRNA Plasmid (h)

sc-43894-SHhGene SilencingPuromycin0
(0)

Lefty shRNA (h) Lentiviral Particles

sc-43894-VhGene SilencingPuromycin0
(0)

Lefty-A siRNA (h)

sc-39789hGene SilencingN/A0
(0)

Lefty-A shRNA Plasmid (h)

sc-39789-SHhGene SilencingPuromycin0
(0)

Lefty-A shRNA (h) Lentiviral Particles

sc-39789-VhGene SilencingPuromycin0
(0)

Lefty-B siRNA (h)

sc-39790hGene SilencingN/A0
(0)

Lefty-B shRNA Plasmid (h)

sc-39790-SHhGene SilencingPuromycin0
(0)

Lefty-B shRNA (h) Lentiviral Particles

sc-39790-VhGene SilencingPuromycin0
(0)

Lefty-1 siRNA (m)

sc-39791mGene SilencingN/A0
(0)

Lefty-1 shRNA Plasmid (m)

sc-39791-SHmGene SilencingPuromycin0
(0)

Lefty-1 shRNA (m) Lentiviral Particles

sc-39791-VmGene SilencingPuromycin0
(0)

Lefty-2 siRNA (m)

sc-39792mGene SilencingN/A0
(0)

Lefty-2 shRNA Plasmid (m)

sc-39792-SHmGene SilencingPuromycin0
(0)

Lefty-2 shRNA (m) Lentiviral Particles

sc-39792-VmGene SilencingPuromycin0
(0)