Date published: 2026-3-17

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LEF Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of LEF Antibodies for investigating lymphoid enhancer-binding factor (LEF) proteins. LEF Antibodies are available for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). LEF proteins function as transcription factors within the Wnt signaling pathway, playing essential roles in cell proliferation, differentiation, and development. Research has shown that LEF proteins are fundamental in embryogenesis and maintaining stem cell properties. Understanding LEF protein activity has become increasingly important as their dysregulation has been linked to various diseases, including cancer. Ongoing research continues to uncover new functions and regulatory mechanisms of LEF proteins in cellular processes. Current investigations focus on how LEF proteins interact with other molecular components in signaling pathways. Exploring LEF protein function may lead to breakthrough therapeutic strategies for various medical conditions. Santa Cruz Biotechnology monoclonal antibodies for LEF proteins enable researchers to advance scientific understanding and potentially develop new therapeutic approaches.

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LEF Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

LEF-1 Antibody (B-10)

sc-374412mouse IgG2a κ61-130 (h)WB, IP, IF, IHC(P), ELISAh
10
(11)

LEF-1 Antibody (B-6)

sc-374522mouse IgG1 κ61-130 (h)WB, IP, IF, IHC(P), ELISAm, r, h
14
(7)

LEF-1 Antibody (2D12)

sc-81470mouse IgG11-85 (h)WB, IPm, r, h
2
(1)

LEF-1 Antibody (REMB1)

sc-56722mouse IgG1FL (h)WB, IP, IF, ELISAm, r, h
1
(2)

LEF CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

LEF-1 CRISPR/Cas9 KO Plasmid (h2)

sc-400643-KO-2hGene KnockoutGFP0
(0)

LEF-1 HDR Plasmid (h2)

sc-400643-HDR-2hHomology Directed RepairPuromycin0
(0)

LEF-1 CRISPR/Cas9 KO Plasmid (m)

sc-421411mGene KnockoutGFP0
(0)

LEF-1 HDR Plasmid (m)

sc-421411-HDRmHomology Directed RepairPuromycin0
(0)

LEF siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

LEF-1 siRNA (h)

sc-35804hGene SilencingN/A
8
(0)

LEF-1 shRNA Plasmid (h)

sc-35804-SHhGene SilencingPuromycin
8
(0)

LEF-1 shRNA (h) Lentiviral Particles

sc-35804-VhGene SilencingPuromycin
8
(0)

LEF-1 siRNA (m)

sc-35805mGene SilencingN/A
4
(0)

LEF-1 shRNA Plasmid (m)

sc-35805-SHmGene SilencingPuromycin
4
(0)

LEF-1 shRNA (m) Lentiviral Particles

sc-35805-VmGene SilencingPuromycin
4
(0)