LEF-1 Antibody (REMB1): sc-56722
- LEF-1 Antibody (REMB1) is a mouse monoclonal IgG1, cited in 1 publications, provided at 100 µg/ml
- raised against full length LEF-1 of human origin
- recommended for detection of β-catenin binding domain of LEF-1 of mouse, rat and human origin by WB, IP, IF and ELISA; non cross-reactive with TCF1 or TCF4
- See LEF-1 (B-10): sc-374412 for LEF-1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for LEF-1 Antibody (REMB1). This work is in progress.
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SEE ALSO...
LEF-1 Antibody (REMB1) is a mouse monoclonal IgG1 antibody that detects LEF-1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). LEF-1, a member of the TCF/LEF family of transcription factors, plays a crucial role in the Wnt signaling pathway, which is essential for various developmental processes and cellular functions. LEF-1 is primarily located in the nucleus, where LEF-1 interacts with β-catenin to regulate the transcription of Wnt target genes. Nuclear localization of LEF-1 allows for precise control of gene expression in response to Wnt signaling, influencing cell fate decisions during embryonic development and tissue homeostasis. Dysregulation of LEF-1 and associated pathways can lead to various diseases, including cancer, highlighting the importance of studying LEF-1 for understanding tumorigenesis and potential therapeutic interventions. Anti-LEF-1 antibody (REMB1) serves as an invaluable tool for researchers investigating the complexities of Wnt signaling and its implications in developmental biology and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LEF-1 Antibody (REMB1) | sc-56722 | 100 µg/ml | $322.00 |