LCE3A Activators
The chemical class referred to as LCE3A Activators encompasses a group of compounds that demonstrate the ability to modulate the activity of the LCE3A gene. LCE3A, or Late Cornified Envelope 3A, is a gene that encodes proteins involved in the formation of the cornified envelope, a structure crucial for maintaining the integrity and barrier function of the skin. Activators of LCE3A are substances capable of enhancing the expression or function of this gene, potentially influencing the synthesis and assembly of proteins within the cornified envelope and thereby affecting the protective properties of the skin.
Identifying compounds as LCE3A Activators typically involves screening processes aimed at evaluating their ability to interact with the regulatory elements of the LCE3A gene or modulate the activity of transcription factors involved in its expression. These activators may act through various mechanisms, such as binding to specific DNA sequences, modifying chromatin structure, or influencing signaling pathways that regulate LCE3A gene expression. Understanding the molecular mechanisms underlying the activation of LCE3A by these compounds can provide insights into the physiological processes involved in skin barrier formation and maintenance. Further research into LCE3A Activators may lead to a deeper understanding of skin biology and potentially unveil novel strategies for promoting skin health and addressing conditions related to skin barrier dysfunction.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
This metabolite of vitamin A plays a crucial role in skin health by regulating cell growth and differentiation, potentially increasing LCE3A expression in the process of epidermal maturation. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Vitamin D3, through its active form, may influence keratinocyte differentiation and skin barrier formation, possibly upregulating LCE3A as part of the skin's adaptive response to environmental factors. | ||||||
Tazarotene | 118292-40-3 | sc-220193 | 10 mg | $103.00 | ||
As a synthetic retinoid, Tazarotene modulates gene expression involved in skin differentiation and may enhance LCE3A expression as part of its mechanism to improve skin barrier function. | ||||||
Salicylic acid | 69-72-7 | sc-203374 sc-203374A sc-203374B | 100 g 500 g 1 kg | $46.00 $92.00 $117.00 | 3 | |
Known for its role in skin care, Salicylic Acid may induce LCE3A expression through its exfoliating properties that trigger skin renewal and barrier repair processes. | ||||||
Glycolic acid solution | 79-14-1 | sc-215102 sc-215102A | 25 g 500 g | $38.00 $60.00 | ||
As an alpha-hydroxy acid, Glycolic Acid promotes exfoliation and skin renewal, potentially upregulating LCE3A expression in the process of epidermal differentiation. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
A form of vitamin B3, Nicotinamide can influence skin barrier function and resilience, potentially upregulating LCE3A as part of its protective effect on the epidermis. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Often used in dandruff shampoos, Zinc Pyrithione may enhance LCE3A expression by affecting keratinocyte turnover and improving skin barrier integrity. | ||||||
Urea | 57-13-6 | sc-29114 sc-29114A sc-29114B | 1 kg 2 kg 5 kg | $30.00 $42.00 $76.00 | 17 | |
Urea is a natural moisturizing factor that can influence skin hydration and barrier function, potentially upregulating LCE3A in the process of skin repair and hydration maintenance. | ||||||
Hyaluronic acid | 9004-61-9 | sc-337865 | 10 mg | $204.00 | ||
As a key molecule in skin hydration, Hyaluronic Acid may influence LCE3A expression through its role in maintaining skin moisture and promoting barrier recovery. | ||||||
Lactic acid | 50-21-5 | sc-215227 sc-215227A | 100 ml 500 ml | $100.00 $175.00 | 1 | |
Lactic Acid, another alpha-hydroxy acid, may stimulate LCE3A expression through its effects on skin hydration and turnover, aiding in the skin's natural barrier restoration processes. | ||||||