Date published: 2026-4-1

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LCE2B Activators

LCE2B Activators represent a specialized class of chemical compounds or molecules that have gained significance within the realm of molecular biology and cellular research. These activators are designed or identified with the specific objective of modulating the activity of the LCE2B gene. LCE2B, or Late Cornified Envelope 2B, is a protein-coding gene found in humans and various organisms. It plays a role in encoding proteins associated with the formation of the late cornified envelope, a structural component of the skin's outermost layer, the stratum corneum.

The study of LCE2B activators is intriguing because it provides researchers with a means to explore the precise role of the LCE2B gene in skin physiology and molecular mechanisms related to skin barrier function. Activation of LCE2B can offer valuable insights into its potential involvement in processes such as epidermal barrier formation, skin protection, and response to environmental stressors. By manipulating the activity of LCE2B through these activators, scientists aim to gain a deeper understanding of the complex molecular pathways and cellular functions that rely on the gene product, thereby contributing to the broader knowledge of skin biology and its role in protecting the body from external factors. Consequently, LCE2B activators serve as crucial tools for researchers dedicated to unraveling the intricate molecular mechanisms that govern skin health and the specific functions played by individual genes in these processes, particularly within the context of skin barrier formation and protection.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Vitamin A

68-26-8sc-280187
sc-280187A
1 g
10 g
$385.00
$2654.00
(2)

A form of vitamin A which can regulate gene expression by activating retinoic acid receptors, potentially influencing skin cell differentiation.

1α,25-Dihydroxyvitamin D3

32222-06-3sc-202877B
sc-202877A
sc-202877C
sc-202877D
sc-202877
50 µg
1 mg
5 mg
10 mg
100 µg
$220.00
$645.00
$1000.00
$1500.00
$440.00
32
(2)

The active form of vitamin D that can modulate gene expression via the vitamin D receptor, with relevance to skin cell function.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

May influence Wnt signaling, which plays a role in skin development and could thus affect LCE2B expression indirectly.

Oltipraz

64224-21-1sc-205777
sc-205777A
500 mg
1 g
$286.00
$622.00
(1)

Activates Nrf2, a transcription factor that responds to oxidative stress and may influence skin barrier gene expression.

Arsenic(III) oxide

1327-53-3sc-210837
sc-210837A
250 g
1 kg
$89.00
$228.00
(0)

Can induce the expression of genes involved in differentiation of keratinocytes, potentially affecting LCE2B.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

A green tea polyphenol that could modulate pathways involved in cell growth and differentiation, influencing epidermal genes.

Benzalkonium chloride

63449-41-2sc-257126
100 g
$81.00
(2)

A skin disinfectant that could potentially trigger a stress response in keratinocytes, possibly affecting LCE2B expression.

Tazarotene

118292-40-3sc-220193
10 mg
$103.00
(0)

A synthetic retinoid that may modulate gene expression in the skin by activating retinoic acid receptors.

Salicylic acid

69-72-7sc-203374
sc-203374A
sc-203374B
100 g
500 g
1 kg
$47.00
$94.00
$119.00
3
(1)

Known to influence skin cell turnover and could potentially affect the expression of differentiation-related genes like LCE2B.