LCE2A Activators
LCE2A activators belong to a specific chemical class designed to modulate the activity of the LCE2A protein. LCE2A, also known as Late Cornified Envelope Protein 2A, is a member of the late cornified envelope (LCE) protein family. These proteins are primarily expressed in the skin and play essential roles in epidermal barrier function and maintenance. LCE2A, specifically, is believed to contribute to the structural integrity of the cornified envelope, a protective layer formed during the terminal differentiation of keratinocytes. The cornified envelope acts as a barrier against environmental stressors, pathogens, and water loss, crucial for maintaining skin health and homeostasis. Although the precise functions of LCE2A are still being elucidated, it is thought to play a role in epidermal barrier function and cutaneous homeostasis.
The investigation into LCE2A activators focuses on understanding the molecular mechanisms underlying their interaction with the LCE2A protein and how this interaction affects epidermal barrier function. These activators may modulate LCE2A activity, influencing the assembly or stability of the cornified envelope and thereby impacting skin barrier function. Understanding the pharmacological properties of LCE2A activators is crucial for deciphering their potential effects on epidermal barrier function and cutaneous health. By delving into the biological functions and regulatory mechanisms of LCE2A, researchers aim to deepen our understanding of skin biology and may uncover novel insights into the molecular pathways governing epidermal barrier formation and maintenance. Continued exploration of LCE2A activators holds promise for advancing our knowledge of skin physiology and may provide insights into new strategies for promoting skin health.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Converts to its active form, calcitriol, which can bind to vitamin D receptors and modulate gene expression, possibly affecting LCE2A. | ||||||
Calcium chloride anhydrous | 10043-52-4 | sc-207392 sc-207392A | 100 g 500 g | $66.00 $262.00 | 1 | |
Calcium ions can act as second messengers, influencing various signaling pathways that may lead to changes in gene expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoids can bind to retinoic acid receptors affecting gene expression in skin differentiation processes. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Influences glycogen synthase kinase 3 (GSK-3) activity, potentially impacting Wnt signaling and gene expression. | ||||||
Oleic Acid | 112-80-1 | sc-200797C sc-200797 sc-200797A sc-200797B | 1 g 10 g 100 g 250 g | $37.00 $104.00 $580.00 $1196.00 | 10 | |
A fatty acid that can integrate into cell membranes, possibly affecting membrane-associated signaling and gene transcription. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc ions can modulate transcription factor activity and could induce gene expression changes. | ||||||
Arachidonic Acid (20:4, n-6) | 506-32-1 | sc-200770 sc-200770A sc-200770B | 100 mg 1 g 25 g | $92.00 $240.00 $4328.00 | 9 | |
A precursor for eicosanoids that may act as signaling molecules, influencing gene expression during inflammation. | ||||||
Hyaluronic acid | 9004-61-9 | sc-337865 | 10 mg | $208.00 | ||
Can interact with cell surface receptors, potentially influencing signaling pathways that regulate gene expression. | ||||||
Glycerol | 56-81-5 | sc-29095A sc-29095 | 100 ml 1 L | $56.00 $153.00 | 12 | |
As a skin humectant, it might affect cell signaling and skin barrier function, potentially altering gene expression. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $44.00 $66.00 $204.00 $831.00 | 6 | |
A form of vitamin B3 that is known to affect various cellular processes including cell signaling and gene transcription. | ||||||