Date published: 2025-12-19

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KRTAP9-L1 Activators

Triiodothyronine plays a significant role in hair growth dynamics and keratin production. Zinc sulfate and copper(II) sulfate, essential trace elements in the body, are integral to the structural development of hair, acting as cofactors for enzymes that stabilize keratin structures, thereby impacting the expression and function of KRTAP9-L1. L-Cysteine is a sulfur-containing amino acid that contributes to the robust disulfide bonds in keratin, essential for its structural stability, directly affecting KRTAP9-L1 integrity within hair fibers. Growth factors such as EGF, which promote keratinocyte proliferation, help in increasing the availability of keratin proteins, including KRTAP9-L1. The active form of vitamin D, 1,25-Dihydroxyvitamin D3, enhances keratinocyte differentiation, which is a pivotal step in the pathway leading to keratin protein expression.

Fatty acids like oleic acid, linoleic acid, and γ-linolenic acid are crucial for maintaining cell membrane fluidity and function, which in turn influences signaling pathways and cellular processes that dictate keratin protein expression, playing a role in the regulation of KRTAP9-L1. Biotin, by facilitating cell growth and the metabolism of amino acids, supports the synthesis of keratin proteins, thus indirectly promoting the synthesis of KRTAP9-L1. Selenium sulfide, by protecting cells from oxidative damage, maintains the health of keratinocytes, which is conducive to the production of keratin proteins.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Retinoic acid, a metabolite of vitamin A, regulates gene expression and keratinization, which can enhance the synthesis of keratin proteins, including KRTAP9-L1.

L-3,3′,5-Triiodothyronine, free acid

6893-02-3sc-204035
sc-204035A
sc-204035B
10 mg
100 mg
250 mg
$40.00
$75.00
$150.00
(1)

T3, the active form of thyroid hormone, modulates transcription of numerous genes involved in hair growth and can upregulate the expression of hair-specific keratin proteins.

Zinc

7440-66-6sc-213177
100 g
$47.00
(0)

Zinc is essential for DNA synthesis and cell division, processes that are fundamental for keratinocyte proliferation. Adequate zinc levels are necessary for keratin protein synthesis, thus influencing KRTAP9-L1 expression.

Copper(II) sulfate

7758-98-7sc-211133
sc-211133A
sc-211133B
100 g
500 g
1 kg
$45.00
$120.00
$185.00
3
(1)

Copper is a cofactor for enzymes involved in the cross-linking of keratin fibers in hair. Sufficient copper levels help maintain the structural integrity of keratin, potentially affecting the function of KRTAP9-L1.

L-Cysteine

52-90-4sc-286072
sc-286072A
sc-286072B
sc-286072C
sc-286072D
25 g
100 g
500 g
5 kg
10 kg
$50.00
$110.00
$440.00
$1128.00
$2135.00
1
(1)

L-Cysteine is an amino acid that contributes to the disulfide bonding in keratin. Providing L-cysteine can support the structural stability and formation of keratin proteins, which includes KRTAP9-L1.

1α,25-Dihydroxyvitamin D3

32222-06-3sc-202877B
sc-202877A
sc-202877C
sc-202877D
sc-202877
50 µg
1 mg
5 mg
10 mg
100 µg
$325.00
$632.00
$1428.00
$2450.00
$400.00
32
(2)

This active form of vitamin D3 influences keratinocyte proliferation and differentiation. By modulating these processes, 1,25-Dihydroxyvitamin D3 can affect the expression of keratin proteins like KRTAP9-L1 in hair follicles.

Oleic Acid

112-80-1sc-200797C
sc-200797
sc-200797A
sc-200797B
1 g
10 g
100 g
250 g
$36.00
$102.00
$569.00
$1173.00
10
(1)

Oleic acid, a fatty acid, is involved in maintaining the integrity of cellular membranes and can influence signal transduction pathways related to cell growth and differentiation, which may include those affecting KRTAP9-L1.

Linoleic Acid

60-33-3sc-200788
sc-200788A
sc-200788B
sc-200788C
100 mg
1 g
5 g
25 g
$33.00
$63.00
$163.00
$275.00
4
(2)

As an essential fatty acid, linoleic acid is integral to cell membrane structure and signaling pathways. Its role in cellular functions could extend to the regulation of keratin protein expression, including KRTAP9-L1.

D-(+)-Biotin

58-85-5sc-204706
sc-204706A
sc-204706B
1 g
5 g
25 g
$40.00
$105.00
$326.00
1
(4)

Biotin supports cell growth and the metabolism of amino acids that are building blocks for protein synthesis. It can indirectly promote the synthesis of keratin proteins such as KRTAP9-L1.

Selenium

7782-49-2sc-250973
50 g
$61.00
1
(1)

Selenium is a trace element that plays a role in the protection of cells from oxidative damage, which may affect keratin expression by influencing the overall health of keratinocytes and thereby the production of proteins like KRTAP9-L1.