Chemicals classified as Krtap31-1 Inhibitors would include a diverse array of compounds that indirectly influence the expression, synthesis, or structural integrity of keratin-associated proteins, specifically Krtap31-1. Retinoic Acid and Genistein can modulate gene expression, possibly altering the abundance of Krtap31-1. Cycloheximide and Actinomycin D act on the protein synthesis machinery, thereby reducing the overall production of proteins, including Krtap31-1. Compounds such as Dithiothreitol and alkylating agents like N-Ethylmaleimide can disrupt the structural conformation of keratin-associated proteins by breaking disulfide bonds or by modifying cysteine residues, respectively. These modifications can compromise the integrity and function of keratin fibers where Krtap31-1 is involved.
Heavy metals like Cadmium Chloride can have a broad impact on cellular processes, including the expression of certain proteins, while Lithium Chloride's influence on GSK-3 activity can indirectly affect the expression and function of numerous proteins. Trichostatin A, through its epigenetic effects, can have a widespread impact on gene expression. Methotrexate, by targeting the folate pathway, can lead to a decrease in nucleotide synthesis and subsequently protein synthesis. Hydroxyurea, by inhibiting ribonucleotide reductase, can impact DNA synthesis and repair mechanisms, possibly leading to changes in the expression levels of proteins like Krtap31-1.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Regulates gene expression and can alter the expression of keratin-associated proteins. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Isoflavone that acts as a tyrosine kinase inhibitor and can affect protein synthesis and expression. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Inhibits eukaryotic protein synthesis and could decrease the synthesis of Krtap31-1. | ||||||
N-Ethylmaleimide | 128-53-0 | sc-202719A sc-202719 sc-202719B sc-202719C sc-202719D | 1 g 5 g 25 g 100 g 250 g | $22.00 $68.00 $210.00 $780.00 $1880.00 | 19 | |
Can alkylate cysteine residues and disrupt the structure of keratin-associated proteins. | ||||||
Cadmium chloride, anhydrous | 10108-64-2 | sc-252533 sc-252533A sc-252533B | 10 g 50 g 500 g | $55.00 $179.00 $345.00 | 1 | |
Heavy metal that can alter protein expression and potentially affect Krtap31-1 levels. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Affects glycogen synthase kinase 3 (GSK-3) activity and can influence protein expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Histone deacetylase inhibitor that can change chromatin structure and gene expression profiles, including those of keratin-associated proteins. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
Antimetabolite that inhibits dihydrofolate reductase and can affect protein synthesis. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Inhibits RNA polymerase and can downregulate protein synthesis, including that of keratin-associated proteins. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
Inhibits ribonucleotide reductase and can affect DNA synthesis and repair, potentially influencing Krtap31-1 expression. | ||||||