Date published: 2025-12-8

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KLC Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of KLC Antibodies for investigating kinesin light chains (KLC) in cellular processes. KLC Antibodies are available for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Kinesin light chains are essential components of the kinesin motor protein complex, playing a vital role in intracellular transport and cargo delivery along microtubules. KLC participates in numerous cellular functions, including cell division, neuronal function, and organelle transport. Research focused on KLC contributes significantly to understanding both normal physiology and disease states. Investigating KLC function can reveal important mechanisms underlying neurodegenerative diseases and conditions related to cellular transport dysfunction. Scientists worldwide utilize KLC monoclonal antibodies to advance cellular biology research and explore molecular pathways. Santa Cruz Biotechnology monoclonal antibodies for KLC research support scientists in making meaningful discoveries that enhance our understanding of cellular transport mechanisms.

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KLC Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

KLC2 Antibody (F-11)

sc-515506mouse IgG2b κ45-62 (h)WB, IP, IF, ELISAm, r, h

new

(1)

KLC1 Antibody (L2)

sc-58776mouse IgG2a κFL (bovine)WB, IP, IF, ELISAm, r, h
4
(5)

KLC3 Antibody (E-7)

sc-398332mouse IgG1 κ171-192 (h)WB, IP, IF, ELISAm, r, h
2
(2)

KLC3 Antibody (F-6)

sc-398492mouse IgG2a κ177-192 (h)WB, IP, IF, ELISAm, r, h
1
(2)

KLC4 Antibody (B-8)

sc-376702mouse IgG1487-540 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(2)

KLC CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

KLC1 CRISPR/Cas9 KO Plasmid (h)

sc-401881hGene KnockoutGFP0
(0)

KLC1 HDR Plasmid (h)

sc-401881-HDRhHomology Directed RepairPuromycin0
(0)

KLC1 Double Nickase Plasmid (h)

sc-401881-NIChGene KnockoutPuromycin0
(0)

KLC1 Double Nickase Plasmid (h2)

sc-401881-NIC-2hGene KnockoutPuromycin0
(0)

KLC1 CRISPR/Cas9 KO Plasmid (m)

sc-421292mGene KnockoutGFP0
(0)

KLC1 HDR Plasmid (m)

sc-421292-HDRmHomology Directed RepairPuromycin0
(0)

KLC1 Double Nickase Plasmid (m)

sc-421292-NICmGene KnockoutPuromycin0
(0)

KLC1 Double Nickase Plasmid (m2)

sc-421292-NIC-2mGene KnockoutPuromycin0
(0)

KLC2 CRISPR/Cas9 KO Plasmid (h)

sc-406012hGene KnockoutGFP0
(0)

KLC2 HDR Plasmid (h)

sc-406012-HDRhHomology Directed RepairPuromycin0
(0)

KLC2 Double Nickase Plasmid (h)

sc-406012-NIChGene KnockoutPuromycin0
(0)

KLC2 Double Nickase Plasmid (h2)

sc-406012-NIC-2hGene KnockoutPuromycin0
(0)

KLC2 CRISPR/Cas9 KO Plasmid (m)

sc-421293mGene KnockoutGFP0
(0)

KLC2 HDR Plasmid (m)

sc-421293-HDRmHomology Directed RepairPuromycin0
(0)

KLC2 Double Nickase Plasmid (m)

sc-421293-NICmGene KnockoutPuromycin0
(0)

KLC2 Double Nickase Plasmid (m2)

sc-421293-NIC-2mGene KnockoutPuromycin0
(0)

KLC3 CRISPR/Cas9 KO Plasmid (h)

sc-409508hGene KnockoutGFP0
(0)

KLC3 HDR Plasmid (h)

sc-409508-HDRhHomology Directed RepairPuromycin0
(0)

KLC3 Double Nickase Plasmid (h)

sc-409508-NIChGene KnockoutPuromycin0
(0)

KLC3 Double Nickase Plasmid (h2)

sc-409508-NIC-2hGene KnockoutPuromycin0
(0)

KLC3 CRISPR/Cas9 KO Plasmid (m)

sc-433213mGene KnockoutGFP0
(0)

KLC3 HDR Plasmid (m)

sc-433213-HDRmHomology Directed RepairPuromycin0
(0)

KLC3 Double Nickase Plasmid (m)

sc-433213-NICmGene KnockoutPuromycin0
(0)

KLC3 Double Nickase Plasmid (m2)

sc-433213-NIC-2mGene KnockoutPuromycin0
(0)

KLC4 CRISPR/Cas9 KO Plasmid (h)

sc-408307hGene KnockoutGFP0
(0)

KLC4 HDR Plasmid (h)

sc-408307-HDRhHomology Directed RepairPuromycin0
(0)

KLC4 Double Nickase Plasmid (h)

sc-408307-NIChGene KnockoutPuromycin0
(0)

KLC4 Double Nickase Plasmid (h2)

sc-408307-NIC-2hGene KnockoutPuromycin0
(0)

KLC4 CRISPR/Cas9 KO Plasmid (m)

sc-428978mGene KnockoutGFP0
(0)

KLC4 HDR Plasmid (m)

sc-428978-HDRmHomology Directed RepairPuromycin0
(0)

KLC4 Double Nickase Plasmid (m)

sc-428978-NICmGene KnockoutPuromycin0
(0)

KLC4 Double Nickase Plasmid (m2)

sc-428978-NIC-2mGene KnockoutPuromycin0
(0)

KLC CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

KLC1 CRISPR Activation Plasmid (h)

sc-401881-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLC1 CRISPR Activation Plasmid (h2)

sc-401881-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLC1 Lentiviral Activation Particles (h)

sc-401881-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLC1 Lentiviral Activation Particles (h2)

sc-401881-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLC1 CRISPR Activation Plasmid (m)

sc-421292-ACTmGene ActivationPuro, Blast, Hygro0
(0)

KLC1 CRISPR Activation Plasmid (m2)

sc-421292-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

KLC1 Lentiviral Activation Particles (m)

sc-421292-LACmGene ActivationPuro, Blast, Hygro0
(0)

KLC1 Lentiviral Activation Particles (m2)

sc-421292-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

KLC2 CRISPR Activation Plasmid (h)

sc-406012-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLC2 CRISPR Activation Plasmid (h2)

sc-406012-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLC2 Lentiviral Activation Particles (h)

sc-406012-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLC2 Lentiviral Activation Particles (h2)

sc-406012-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLC2 CRISPR Activation Plasmid (m)

sc-421293-ACTmGene ActivationPuro, Blast, Hygro0
(0)

KLC2 CRISPR Activation Plasmid (m2)

sc-421293-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

KLC2 Lentiviral Activation Particles (m)

sc-421293-LACmGene ActivationPuro, Blast, Hygro0
(0)

KLC2 Lentiviral Activation Particles (m2)

sc-421293-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

KLC3 CRISPR Activation Plasmid (h)

sc-409508-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLC3 CRISPR Activation Plasmid (h2)

sc-409508-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLC3 Lentiviral Activation Particles (h)

sc-409508-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLC3 Lentiviral Activation Particles (h2)

sc-409508-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLC3 CRISPR Activation Plasmid (m)

sc-433213-ACTmGene ActivationPuro, Blast, Hygro0
(0)

KLC3 CRISPR Activation Plasmid (m2)

sc-433213-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

KLC3 Lentiviral Activation Particles (m)

sc-433213-LACmGene ActivationPuro, Blast, Hygro0
(0)

KLC3 Lentiviral Activation Particles (m2)

sc-433213-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

KLC4 CRISPR Activation Plasmid (h)

sc-408307-ACThGene ActivationPuro, Blast, Hygro0
(0)

KLC4 CRISPR Activation Plasmid (h2)

sc-408307-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

KLC4 Lentiviral Activation Particles (h)

sc-408307-LAChGene ActivationPuro, Blast, Hygro0
(0)

KLC4 Lentiviral Activation Particles (h2)

sc-408307-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

KLC4 CRISPR Activation Plasmid (m)

sc-428978-ACTmGene ActivationPuro, Blast, Hygro0
(0)

KLC4 CRISPR Activation Plasmid (m2)

sc-428978-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

KLC4 Lentiviral Activation Particles (m)

sc-428978-LACmGene ActivationPuro, Blast, Hygro0
(0)

KLC4 Lentiviral Activation Particles (m2)

sc-428978-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

KLC siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

KLC1 siRNA (h)

sc-43880hGene SilencingN/A
2
(0)

KLC1 shRNA Plasmid (h)

sc-43880-SHhGene SilencingPuromycin
2
(0)

KLC1 shRNA (h) Lentiviral Particles

sc-43880-VhGene SilencingPuromycin
2
(0)

KLC1 siRNA (m)

sc-43881mGene SilencingN/A
2
(0)

KLC1 shRNA Plasmid (m)

sc-43881-SHmGene SilencingPuromycin
2
(0)

KLC1 shRNA (m) Lentiviral Particles

sc-43881-VmGene SilencingPuromycin
2
(0)

KLC2 siRNA (h)

sc-96580hGene SilencingN/A
1
(0)

KLC2 shRNA Plasmid (h)

sc-96580-SHhGene SilencingPuromycin
1
(0)

KLC2 shRNA (h) Lentiviral Particles

sc-96580-VhGene SilencingPuromycin
1
(0)

KLC2 siRNA (m)

sc-146492mGene SilencingN/A
1
(0)

KLC2 shRNA Plasmid (m)

sc-146492-SHmGene SilencingPuromycin
1
(0)

KLC2 shRNA (m) Lentiviral Particles

sc-146492-VmGene SilencingPuromycin
1
(0)

KLC3 siRNA (h)

sc-97086hGene SilencingN/A0
(0)

KLC3 shRNA Plasmid (h)

sc-97086-SHhGene SilencingPuromycin0
(0)

KLC3 shRNA (h) Lentiviral Particles

sc-97086-VhGene SilencingPuromycin0
(0)

KLC4 siRNA (h)

sc-95336hGene SilencingN/A0
(0)

KLC4 shRNA Plasmid (h)

sc-95336-SHhGene SilencingPuromycin0
(0)

KLC4 shRNA (h) Lentiviral Particles

sc-95336-VhGene SilencingPuromycin0
(0)

KLC4 siRNA (m)

sc-146494mGene SilencingN/A0
(0)

KLC4 shRNA Plasmid (m)

sc-146494-SHmGene SilencingPuromycin0
(0)

KLC4 shRNA (m) Lentiviral Particles

sc-146494-VmGene SilencingPuromycin0
(0)