KIF21A Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Colchicine disrupts microtubule polymerization by binding to tubulin, which is a primary component of microtubules. KIF21A, as a kinesin motor protein, relies on microtubules for its movement; thus, colchicine's action on microtubules can inhibit KIF21A's function. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Paclitaxel stabilizes microtubules and prevents their depolymerization, which is expected to hinder the motor activity of KIF21A by reducing the dynamicity of microtubules, a necessary feature for KIF21A's proper function. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $230.00 $450.00 $1715.00 $2900.00 | 4 | |
Vinblastine binds to tubulin and inhibits microtubule formation, which can inhibit KIF21A by disrupting the microtubule tracks required for its motor function. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole disrupts microtubule polymerization, which would inhibit the function of KIF21A by removing its structural substrate needed for motor activity. | ||||||
Podophyllotoxin | 518-28-5 | sc-204853 | 100 mg | $82.00 | 1 | |
Podophyllotoxin binds to tubulin and inhibits its polymerization into microtubules, which would lead to the inhibition of KIF21A by preventing it from performing its motor function on microtubules. | ||||||
Eribulin | 253128-41-5 | sc-507547 | 5 mg | $865.00 | ||
Eribulin inhibits the growth phase of microtubule dynamics which can inhibit KIF21A function by disrupting the microtubule networks that are essential for its motor activity. | ||||||
Colcemid | 477-30-5 | sc-202550A sc-202550 sc-202550B sc-202550C sc-202550D sc-202550E | 1 mg 5 mg 10 mg 50 mg 100 mg 500 mg | $67.00 $159.00 $312.00 $928.00 $1856.00 $6706.00 | 7 | |
Demecolcine, a colchicine derivative, binds tubulin and prevents microtubule polymerization, which would inhibit KIF21A by disrupting the microtubule tracks it requires to function. | ||||||
Griseofulvin | 126-07-8 | sc-202171A sc-202171 sc-202171B | 5 mg 25 mg 100 mg | $83.00 $216.00 $586.00 | 4 | |
Griseofulvin disrupts microtubule function by binding to polymerized microtubules, potentially inhibiting KIF21A by destabilizing the microtubule structures necessary for its activity. | ||||||
Albendazole | 54965-21-8 | sc-210771 | 100 mg | $209.00 | 1 | |
Albendazole inhibits microtubule polymerization, which could lead to functional inhibition of KIF21A by preventing it from moving along the microtubule tracks. | ||||||
Mebendazole | 31431-39-7 | sc-204798 sc-204798A | 5 g 25 g | $45.00 $87.00 | 2 | |
Mebendazole causes selective disruption of microtubule polymerization, which can inhibit KIF21A by impairing the structural framework required for its motor function. | ||||||