KCNQ1 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Chromanol 293B | 163163-23-3 | sc-203889 sc-203889A | 10 mg 50 mg | $182.00 $774.00 | 1 | |
Chromanol 293B, a selective blocker of KCNQ1, inhibits the voltage-gated potassium channel involved in cardiac repolarization. It modulates the KCNQ1 channel by interacting with its pore-forming subunit, disrupting ion flux and influencing cardiac action potential duration. | ||||||
Linopirdine dihydrochloride | 113168-57-3 | sc-204058 sc-204058A | 10 mg 50 mg | $165.00 $700.00 | ||
Linopirdine, a KCNQ1 blocker, impacts the channel by inhibiting its conductance, influencing the repolarization phase of the cardiac action potential. Through its interaction with KCNQ1, it alters potassium ion flow, leading to changes in membrane potential and cardiac excitability. | ||||||
Clofilium tosylate | 92953-10-1 | sc-391228 sc-391228A | 25 mg 100 mg | $437.00 $1040.00 | 1 | |
Clofilium, known for its inhibition of KCNQ1, modulates the channel's activity by interacting with its pore-forming subunit. By impeding potassium flux, it alters the repolarization phase of the cardiac action potential, influencing membrane potential and cellular excitability in cardiac tissues. | ||||||
DPO-1 | 43077-30-1 | sc-203570 sc-203570A | 10 mg 50 mg | $170.00 $715.00 | ||
DPO-1, a selective KCNQ1 inhibitor, impacts the channel's function by binding to specific sites, disrupting potassium ion conductance. Its modulation of KCNQ1 alters the repolarization phase of the cardiac action potential, influencing cellular excitability and membrane potential in cardiac tissues. | ||||||
JNJ 303 | 878489-28-2 | sc-361217 sc-361217A | 10 mg 50 mg | $412.00 $1686.00 | ||
JNJ-303, a selective KCNQ1 inhibitor, influences the channel by targeting specific regions involved in potassium ion transport. By impeding ion flux, it modulates the repolarization phase of the cardiac action potential, leading to alterations in membrane potential and cellular excitability in cardiac tissues. | ||||||
4-Chlorophenoxyacetic acid | 122-88-3 | sc-238822 | 250 g | $68.00 | ||
4-Chlorophenoxyacetic acid indirectly modulates KCNQ1 by affecting cellular signaling pathways involved in channel regulation. Its impact on downstream cascades leads to alterations in KCNQ1 activity, influencing the repolarization phase of the cardiac action potential and cellular excitability in cardiac tissues. | ||||||
Linarine | 480-36-4 | sc-488995 sc-488995A sc-488995B sc-488995C | 5 mg 25 mg 50 mg 100 mg | $430.00 $490.00 $740.00 $1240.00 | ||
Linarin, a KCNQ1 modulator, exerts its effects through interactions with signaling pathways associated with channel activity. By indirectly influencing KCNQ1, it alters potassium ion conductance, impacting the repolarization phase of the cardiac action potential and cellular excitability in cardiac tissues. | ||||||