JAM-C Inhibitors
JAM-C inhibitors belong to a specific chemical class of compounds designed to modulate the activity of JAM-C, also known as junctional adhesion molecule-C. JAM-C is a cell adhesion molecule that plays crucial roles in various cellular processes, including cell migration, angiogenesis, and inflammation. These inhibitors are designed to selectively target JAM-C and interfere with its cellular functions. The mechanism of action of JAM-C inhibitors typically involves binding to specific regions of JAM-C, disrupting its interactions with other proteins, or blocking its signaling pathways. By inhibiting JAM-C, these compounds may impact cellular adhesion and migration processes, as well as the formation of new blood vessels during angiogenesis.
Researchers use JAM-C inhibitors to study the functional roles of JAM-C in different cellular contexts and to explore its potential as a target for research purposes. Understanding the structural characteristics and mechanisms of JAM-C inhibitors is crucial for advancing knowledge in this area and may have broader implications for future research in cell adhesion and inflammation-related processes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a broad-spectrum inhibitor that has been reported to interact with JAM-C and affect its cellular functions. | ||||||
Ibrutinib | 936563-96-1 | sc-483194 | 10 mg | $156.00 | 5 | |
Ibrutinib is a BTK inhibitor that has been studied for its potential effects on JAM-C in certain experimental models. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Velcade is a proteasome inhibitor that has been reported to affect JAM-C expression and function in certain cellular contexts. | ||||||
Tyrphostin B42 | 133550-30-8 | sc-3556 | 5 mg | $26.00 | 4 | |
AG-490 is a JAK2 inhibitor that has been investigated for its potential impact on JAM-C signaling. | ||||||
Emodin | 518-82-1 | sc-202601 sc-202601A sc-202601B | 50 mg 250 mg 15 g | $105.00 $214.00 $6255.00 | 2 | |
Emodin is a natural compound that has been studied for its potential effects on JAM-C in certain cellular processes. | ||||||
Ruxolitinib | 941678-49-5 | sc-364729 sc-364729A sc-364729A-CW | 5 mg 25 mg 25 mg | $251.00 $500.00 $547.00 | 16 | |
Ruxolitinib is a JAK1/2 inhibitor that has been reported to affect JAM-C expression and function in certain experimental models. | ||||||
Triciribine | 35943-35-2 | sc-200661 sc-200661A | 1 mg 5 mg | $104.00 $141.00 | 14 | |
Triciribine is a compound that has been studied for its potential inhibitory effects on JAM-C and its involvement in cell adhesion. | ||||||
SB202190 hydrochloride | 350228-36-3 | sc-222294 sc-222294A | 1 mg 5 mg | $131.00 $505.00 | 13 | |
SB202190 is a p38 MAPK inhibitor that has been investigated for its potential impact on JAM-C signaling. | ||||||