Iws1 Activators constitute a distinct category of chemical compounds specifically formulated to target and enhance the activity of the Iws1 protein. Iws1, an acronym for "Interacts with Spt6", is recognized as a critical component in the regulation of gene expression at the transcriptional level. It is known to interact with Spt6, a histone chaperone, playing a significant role in chromatin structure and function. This interaction is vital for the proper transcription of genes, as it aids in the maintenance of chromatin structure, ensuring that the DNA is correctly packaged and accessible for transcription. Iws1 is also implicated in various other cellular processes, including mRNA export and processing. Iws1 Activators are designed to bind to this protein, potentially altering its conformation, stability, or its interaction with other cellular components, such as Spt6 and RNA polymerase II. Such interactions are crucial as they can modulate the natural behavior and function of Iws1 within the cell, impacting gene expression and chromatin dynamics.
The exploration of Iws1 Activators is a significant focus within molecular biology and genetics, given the fundamental role of Iws1 in gene expression. These activators, typically small molecular compounds, are crafted to bind specifically to Iws1, inducing alterations in its activity. The exact mechanism through which these activators exert their effects depends on their chemical structure and the nature of their interaction with Iws1. By binding to Iws1, these activators can influence how the protein interacts with other key components involved in transcription, such as Spt6 and RNA polymerase II. This can lead to a cascade of reactions within the cell, altering processes related to transcription regulation, chromatin remodeling, and mRNA processing. Research in this field focuses on understanding the intricate network of protein interactions that govern gene expression and chromatin dynamics. Insights gained from studying Iws1 Activators contribute to a broader understanding of the molecular mechanisms underlying transcriptional regulation and the complex interplay of factors involved in the control of gene expression.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
A histone deacetylase inhibitor that may induce hyperacetylation of histones, potentially leading to a more open chromatin state and increased transcription. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
A potent histone deacetylase inhibitor that may alter gene expression by changing the chromatin structure. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
A hormone that can bind to and activate estrogen receptors, potentially affecting the transcription of responsive genes. | ||||||
Mifepristone | 84371-65-3 | sc-203134 | 100 mg | $60.00 | 17 | |
Known to bind to glucocorticoid receptors as an antagonist, which may influence the expression of glucocorticoid-responsive genes. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
An inhibitor of N-linked glycosylation which can induce ER stress and potentially influence expression of stress-response genes. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Known to inhibit lysosomal function and autophagy, potentially affecting cellular stress pathways and gene expression. | ||||||
Cobalt(II) chloride | 7646-79-9 | sc-252623 sc-252623A | 5 g 100 g | $63.00 $173.00 | 7 | |
A chemical that can mimic hypoxia and may induce the expression of hypoxia-responsive genes. | ||||||
Cadmium chloride, anhydrous | 10108-64-2 | sc-252533 sc-252533A sc-252533B | 10 g 50 g 500 g | $55.00 $179.00 $345.00 | 1 | |
A heavy metal that can induce cellular stress responses, potentially leading to altered expression of certain genes. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
A polyphenol that can activate sirtuin pathways and influence the transcription of various genes associated with stress response and metabolism. | ||||||