IscU1 Activators
The class of IscU1 activators encompasses a diverse array of chemicals that can potentially modulate the activity of IscU1, a crucial player in iron-sulfur cluster biogenesis. These activators, either directly or indirectly, influence the function of IscU1 and contribute to cellular homeostasis. One category of IscU1 activators includes reducing agents such as DTT and glutathione. These compounds can potentially act as direct activators by providing thiol groups, enhancing the stability and functionality of IscU1 in facilitating iron-sulfur cluster assembly. Additionally, chelating agents like 2,3-dimercaptopropanol can directly influence the metal cofactor environment of IscU1, potentially enhancing its role in iron-sulfur cluster biogenesis. Indirect activators of IscU1 include compounds like ferric citrate, lipoic acid, and sulfur. Ferric citrate serves as a source of iron, indirectly impacting IscU1 by influencing iron homeostasis. Lipoic acid, involved in mitochondrial metabolism, may indirectly activate IscU1 by participating in redox reactions and influencing pathways associated with iron-sulfur cluster assembly. Elemental sulfur, as another indirect activator, serves as a precursor for sulfur-containing compounds crucial for IscU1 function.
Furthermore, compounds like Nifedipine and sodium nitroprusside can influence cellular signaling pathways, indirectly affecting IscU1 expression or activity in the context of iron-sulfur cluster biogenesis. NADH, a coenzyme involved in redox reactions, could also act as a direct or indirect activator by modulating cellular redox processes. In summary, the diverse IscU1 activators exert their effects through various mechanisms, either directly enhancing IscU1 stability or indirectly influencing pathways associated with iron-sulfur cluster biogenesis. Understanding the intricate interplay between these chemicals and IscU1 provides valuable insights into the regulation of cellular processes related to iron-sulfur cluster assembly.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Iron(III) citrate | 3522-50-7 | sc-286019 sc-286019A | 100 g 250 g | $45.00 $85.00 | ||
Ferric citrate, a source of iron, may indirectly activate IscU1 by influencing iron homeostasis. Iron is a crucial cofactor for IscU1 function, and supplementation with ferric citrate could potentially enhance iron availability, leading to increased IscU1 activity and its involvement in iron-sulfur cluster assembly. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
Lipoic acid is involved in mitochondrial energy metabolism and may act as an indirect activator of IscU1. By participating in redox reactions and serving as a cofactor, lipoic acid could influence cellular pathways associated with IscU1, potentially enhancing its expression or activity in the context of iron-sulfur cluster biogenesis. | ||||||
Sulfur | 7704-34-9 | sc-215933 sc-215933A | 500 g 2 kg | $51.00 $158.00 | ||
Elemental sulfur may serve as a precursor for sulfur-containing compounds involved in iron-sulfur cluster biogenesis. As a potential indirect activator of IscU1, sulfur contributes to the cellular pool of sulfur, influencing pathways related to IscU1 function and promoting the assembly of iron-sulfur clusters. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $58.00 $170.00 | 15 | |
Nifedipine, a calcium channel blocker, may indirectly impact IscU1 by modulating calcium-dependent signaling pathways. Calcium signaling is implicated in various cellular processes, and Nifedipine could potentially influence these pathways, indirectly affecting IscU1 activity in the context of iron-sulfur cluster biogenesis. | ||||||
Glutathione, reduced | 70-18-8 | sc-29094 sc-29094A | 10 g 1 kg | $76.00 $2050.00 | 8 | |
Glutathione, a tripeptide thiol, may act as a direct or indirect activator of IscU1. As a reducing agent, glutathione can potentially enhance the stability and functionality of IscU1 by providing thiol groups. Additionally, glutathione may influence cellular redox status, indirectly impacting IscU1 activity and its role in iron-sulfur cluster biogenesis. | ||||||
Citric Acid, Anhydrous | 77-92-9 | sc-211113 sc-211113A sc-211113B sc-211113C sc-211113D | 500 g 1 kg 5 kg 10 kg 25 kg | $49.00 $108.00 $142.00 $243.00 $586.00 | 1 | |
Citric acid, a tricarboxylic acid, may indirectly activate IscU1 by participating in cellular metabolic pathways. As a component of the citric acid cycle, citric acid influences various metabolic processes, potentially affecting IscU1 expression or activity in the context of iron-sulfur cluster biogenesis. | ||||||
NADH disodium salt | 606-68-8 | sc-205762 sc-205762A | 500 mg 1 g | $89.00 $127.00 | 3 | |
NADH, a coenzyme involved in redox reactions, may act as a direct or indirect activator of IscU1. By participating in cellular redox processes, NADH could directly influence IscU1 function or indirectly impact its activity by modulating cellular redox status, thereby affecting iron-sulfur cluster biogenesis. | ||||||
Sodium nitroprusside dihydrate | 13755-38-9 | sc-203395 sc-203395A sc-203395B | 1 g 5 g 100 g | $42.00 $83.00 $155.00 | 7 | |
Sodium nitroferricyanide, a nitric oxide donor, may indirectly activate IscU1 by influencing cellular signaling pathways. Nitric oxide is involved in various cellular processes, and sodium nitroprusside could potentially modulate these pathways, indirectly affecting IscU1 expression or activity in the context of iron-sulfur cluster biogenesis. | ||||||
Ammonium Sulfate | 7783-20-2 | sc-29085A sc-29085 sc-29085B sc-29085C sc-29085D sc-29085E | 500 g 1 kg 2 kg 5 kg 10 kg 22.95 kg | $10.00 $20.00 $30.00 $40.00 $60.00 $100.00 | 9 | |
Ammonium sulfate, a source of ammonium ions, may act as a potential indirect activator of IscU1. Ammonium ions are involved in nitrogen metabolism and could influence cellular pathways associated with IscU1, indirectly impacting its expression or activity in the context of iron-sulfur cluster biogenesis. | ||||||