Date published: 2026-5-24

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IRSp53 Antibodies

Santa Cruz Biotechnology features a diverse variety of IRSp53 monoclonal antibodies for research focused on understanding IRSp53 protein functions. IRSp53 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). IRSp53, or insulin receptor substrate p53, is a critical protein involved in actin cytoskeleton remodeling and cell signaling pathways. IRSp53 plays a significant role in neuronal development and synaptic function, making it essential for understanding neurobiology and related disorders. Research has shown that IRSp53 influences cellular morphology through its interaction with membrane dynamics and cytoskeletal components. IRSp53 has been implicated in cancer progression, highlighting its importance in tumor biology and potential therapeutic targets. Scientists studying cell migration and membrane dynamics frequently utilize IRSp53 monoclonal antibodies to advance their research. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to make meaningful contributions to scientific understanding of cellular processes and disease mechanisms.

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IRSp53 Antibodies

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IRSp53 Antibody (46)

sc-136470mouse IgG2a κ200-322 (h)WB, IPm, r, h
3
(3)

IRSp53 CRISPR Knockout, HDR and Double Nickase Plasmids

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IRSp53 Double Nickase Plasmid (h)

sc-403072-NIChGene KnockoutPuromycin0
(0)

IRSp53 CRISPR Activation Products

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IRSp53 CRISPR Activation Plasmid (h)

sc-403072-ACThGene ActivationPuro, Blast, Hygro0
(0)

IRSp53 CRISPR Activation Plasmid (h2)

sc-403072-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

IRSp53 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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IRSp53 siRNA (h)

sc-60863hGene SilencingN/A
1
(0)

IRSp53 shRNA Plasmid (h)

sc-60863-SHhGene SilencingPuromycin
1
(0)

IRSp53 shRNA (h) Lentiviral Particles

sc-60863-VhGene SilencingPuromycin
1
(0)

IRSp53 siRNA (m)

sc-60864mGene SilencingN/A0
(0)

IRSp53 shRNA Plasmid (m)

sc-60864-SHmGene SilencingPuromycin0
(0)

IRSp53 shRNA (m) Lentiviral Particles

sc-60864-VmGene SilencingPuromycin0
(0)

IRSp53 siRNA (r)

sc-270674rGene SilencingN/A0
(0)

IRSp53 shRNA Plasmid (r)

sc-270674-SHrGene SilencingPuromycin0
(0)

IRSp53 shRNA (r) Lentiviral Particles

sc-270674-VrGene SilencingPuromycin0
(0)