Date published: 2026-6-6

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IQGAP1 Activators

Common IQGAP1 Activators include, but are not limited to PMA CAS 16561-29-8, Lipopolysaccharide, E. coli O55:B5 CAS 93572-42-0, Insulin CAS 11061-68-0, Forskolin CAS 66575-29-9 and α-Estradiol CAS 57-91-0.

IQGAP1 (IQ Motif Containing GTPase Activating Protein 1) is a multifunctional scaffold protein that interacts with various proteins to regulate several cellular processes, including cell adhesion, migration, and signaling. IQGAP1 Activators are a class of chemical compounds or molecules that influence the activity of IQGAP1, which stands for IQ motif-containing GTPase-activating protein 1. IQGAP1 is a versatile and multifunctional protein that plays a central role in various cellular processes, primarily by acting as a scaffold protein involved in protein-protein interactions. It is found in a wide range of cell types and is particularly prominent in the cytoskeleton-rich regions of cells, where it regulates processes like cell adhesion, cell motility, and cell signaling.

Activation of IQGAP1 involves various mechanisms, including changes in its conformation and interactions with other proteins. IQGAP1 activators can modulate its functions, influencing its role as a scaffold in cellular processes. These activators are essential for understanding the intricate regulatory mechanisms within cells. Insights gained from studying IQGAP1 activation can contribute to a deeper understanding of cellular physiology and inform future research into diseases or conditions where dysregulation of IQGAP1-related pathways may play a role.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

Known to activate protein kinase C, which might influence IQGAP1 expression or activity.

Lipopolysaccharide, E. coli O55:B5

93572-42-0sc-221855
sc-221855A
sc-221855B
sc-221855C
10 mg
25 mg
100 mg
500 mg
$98.00
$171.00
$425.00
$1560.00
12
(2)

Stimulates immune cells and can activate various signaling pathways, potentially influencing IQGAP1.

Insulin

11061-68-0sc-29062
sc-29062A
sc-29062B
100 mg
1 g
10 g
$156.00
$1248.00
$12508.00
82
(1)

Modulates various cellular signaling pathways, which might affect IQGAP1 expression.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Activates adenylate cyclase, increasing cAMP levels, which might influence IQGAP1 expression.

α-Estradiol

57-91-0sc-204425
50 mg
$71.00
1
(1)

Hormone that influences various cellular processes; its effect on IQGAP1 is less defined.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

A glucocorticoid that can modulate various cellular responses, potentially influencing IQGAP1.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

mTOR inhibitor that influences various signaling pathways, po