Date published: 2025-10-22

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INSM Antibodies

Santa Cruz Biotechnology provides a broad selection of INSM Antibodies for investigating insulinoma-associated protein 1 (INSM1) in research applications. Monoclonal INSM Antibodies are validated for multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). INSM1 functions as a transcription factor with essential roles in neuroendocrine differentiation and appears predominantly in neuroendocrine tumors. Understanding INSM1 regulation provides critical insights into neuroendocrine cell development and function, establishing INSM1 as a key marker for tumor research and diagnosis. INSM1 research advances knowledge in tumor biology while identifying potential therapeutic approaches. Investigating INSM1 expression patterns helps reveal mechanisms underlying neuroendocrine tumor development and progression. Detailed characterization of INSM1 activity contributes to understanding cellular signaling networks in both normal and disease states. Research utilizing INSM1 monoclonal antibodies from Santa Cruz Biotechnology continues to advance scientific understanding of neuroendocrine development and disease mechanisms.

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INSM Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

INSM1 Antibody (A-8)

sc-271408mouse IgG1 κ81-125 (h)WB, IP, IF, IHC(P), ELISAm, r, h
125
(11)

INSM1 Antibody (C-1)

sc-377428mouse IgG1 κ97-135 (h)WB, IP, IF, ELISAm, r, h
6
(2)

INSM CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

INSM1 CRISPR/Cas9 KO Plasmid (h)

sc-402424hGene KnockoutGFP0
(0)

INSM1 HDR Plasmid (h)

sc-402424-HDRhHomology Directed RepairPuromycin0
(0)

INSM1 Double Nickase Plasmid (h)

sc-402424-NIChGene KnockoutPuromycin0
(0)

INSM1 Double Nickase Plasmid (h2)

sc-402424-NIC-2hGene KnockoutPuromycin0
(0)

INSM1 CRISPR/Cas9 KO Plasmid (m)

sc-424742mGene KnockoutGFP0
(0)

INSM1 HDR Plasmid (m)

sc-424742-HDRmHomology Directed RepairPuromycin0
(0)

INSM1 Double Nickase Plasmid (m)

sc-424742-NICmGene KnockoutPuromycin0
(0)

INSM1 Double Nickase Plasmid (m2)

sc-424742-NIC-2mGene KnockoutPuromycin0
(0)

INSM2 CRISPR/Cas9 KO Plasmid (h)

sc-410204hGene KnockoutGFP0
(0)

INSM2 HDR Plasmid (h)

sc-410204-HDRhHomology Directed RepairPuromycin0
(0)

INSM2 Double Nickase Plasmid (h)

sc-410204-NIChGene KnockoutPuromycin0
(0)

INSM2 Double Nickase Plasmid (h2)

sc-410204-NIC-2hGene KnockoutPuromycin0
(0)

INSM2 CRISPR/Cas9 KO Plasmid (m)

sc-425323mGene KnockoutGFP0
(0)

INSM2 HDR Plasmid (m)

sc-425323-HDRmHomology Directed RepairPuromycin0
(0)

INSM2 Double Nickase Plasmid (m)

sc-425323-NICmGene KnockoutPuromycin0
(0)

INSM2 Double Nickase Plasmid (m2)

sc-425323-NIC-2mGene KnockoutPuromycin0
(0)

INSM CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

INSM1 CRISPR Activation Plasmid (h)

sc-402424-ACThGene ActivationPuro, Blast, Hygro0
(0)

INSM1 CRISPR Activation Plasmid (h2)

sc-402424-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

INSM1 Lentiviral Activation Particles (h)

sc-402424-LAChGene ActivationPuro, Blast, Hygro0
(0)

INSM1 Lentiviral Activation Particles (h2)

sc-402424-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

INSM1 CRISPR Activation Plasmid (m)

sc-424742-ACTmGene ActivationPuro, Blast, Hygro0
(0)

INSM1 CRISPR Activation Plasmid (m2)

sc-424742-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

INSM1 Lentiviral Activation Particles (m)

sc-424742-LACmGene ActivationPuro, Blast, Hygro0
(0)

INSM1 Lentiviral Activation Particles (m2)

sc-424742-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

INSM2 CRISPR Activation Plasmid (h)

sc-410204-ACThGene ActivationPuro, Blast, Hygro0
(0)

INSM2 CRISPR Activation Plasmid (h2)

sc-410204-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

INSM2 Lentiviral Activation Particles (h)

sc-410204-LAChGene ActivationPuro, Blast, Hygro0
(0)

INSM2 Lentiviral Activation Particles (h2)

sc-410204-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

INSM2 CRISPR Activation Plasmid (m)

sc-425323-ACTmGene ActivationPuro, Blast, Hygro0
(0)

INSM2 CRISPR Activation Plasmid (m2)

sc-425323-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

INSM2 Lentiviral Activation Particles (m)

sc-425323-LACmGene ActivationPuro, Blast, Hygro0
(0)

INSM2 Lentiviral Activation Particles (m2)

sc-425323-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

INSM siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

INSM1 siRNA (h)

sc-72309hGene SilencingN/A
2
(0)

INSM1 shRNA Plasmid (h)

sc-72309-SHhGene SilencingPuromycin
2
(0)

INSM1 shRNA (h) Lentiviral Particles

sc-72309-VhGene SilencingPuromycin
2
(0)

INSM1 siRNA (m)

sc-72310mGene SilencingN/A0
(0)

INSM1 shRNA Plasmid (m)

sc-72310-SHmGene SilencingPuromycin0
(0)

INSM1 shRNA (m) Lentiviral Particles

sc-72310-VmGene SilencingPuromycin0
(0)

INSM2 siRNA (h)

sc-92409hGene SilencingN/A0
(0)

INSM2 shRNA Plasmid (h)

sc-92409-SHhGene SilencingPuromycin0
(0)

INSM2 shRNA (h) Lentiviral Particles

sc-92409-VhGene SilencingPuromycin0
(0)

INSM2 siRNA (m)

sc-146244mGene SilencingN/A0
(0)

INSM2 shRNA Plasmid (m)

sc-146244-SHmGene SilencingPuromycin0
(0)

INSM2 shRNA (m) Lentiviral Particles

sc-146244-VmGene SilencingPuromycin0
(0)