INF2 Activators
INF2 Activators are chemical compounds that are associated with the modulation of INF2 (Inverted Formin 2) function. INF2, being a pivotal component of the formin family, dictates actin polymerization and the subsequent dynamics of the cytoskeleton. This unique role means that the cellular operations involving INF2 can be indirectly activated by influencing the broader cytoskeletal milieu and related actin dynamics.
Jasplakinolide, for instance, has the capability to stabilize actin filaments, which has implications on the actin dynamics and by extension, INF2-mediated processes. On the other hand, Phalloidin anchors and stabilizes actin filaments, a process that may indirectly touch upon INF2's responsibilities. SMIFH2, a formin inhibitor, holds the potential to modify INF2 activity directly. Microtubules, a critical component of the cytoskeleton, can be disrupted by Nocodazole or stabilized by Taxol (Paclitaxel), both of which can influence actin dynamics and INF2. Blebbistatin, by inhibiting myosin II, affects cell contractility, with possible implications for INF2 pathways. Lastly, Y-27632, a ROCK inhibitor, and ML-7, an inhibitor of myosin light chain kinase (MLCK), both touch upon actin-myosin contractility and can indirectly influence the functions of INF2.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
Stabilizes actin filaments and can affect actin dynamics potentially influencing INF2-mediated processes. | ||||||
Phalloidin | 17466-45-4 | sc-202763 | 1 mg | $234.00 | 33 | |
Binds and stabilizes actin filaments, potentially influencing processes where INF2 is involved. | ||||||
SMIFH2 | 340316-62-3 | sc-507273 | 5 mg | $140.00 | ||
Formin inhibitor which directly affects formins, potentially modulating INF2 activity. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Disrupts microtubules, which can influence actin dynamics and potentially INF2 function indirectly. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Stabilizes microtubules, indirectly influencing actin dynamics and potentially INF2 roles. | ||||||
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $183.00 $313.00 $464.00 $942.00 $1723.00 | 7 | |
Inhibits myosin II, and while mainly affecting contractility, can indirectly influence INF2 pathways. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
ROCK inhibitor that affects actin-myosin contractility, possibly influencing INF2 indirectly. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $91.00 $267.00 | 13 | |
Inhibits myosin light chain kinase (MLCK), which can indirectly affect INF2 by altering actin dynamics. | ||||||