IL-1 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Suramin sodium | 129-46-4 | sc-507209 sc-507209F sc-507209A sc-507209B sc-507209C sc-507209D sc-507209E | 50 mg 100 mg 250 mg 1 g 10 g 25 g 50 g | $149.00 $210.00 $714.00 $2550.00 $10750.00 $21410.00 $40290.00 | 5 | |
Suramin sodium exhibits unique interactions with interleukin-1 (IL-1) by modulating its receptor binding and downstream signaling pathways. Its structure allows for the formation of non-covalent interactions, influencing the conformational dynamics of IL-1 receptors. This compound's ability to disrupt protein-protein interactions enhances its efficacy in altering inflammatory responses. Additionally, its solubility properties facilitate its distribution in biological systems, impacting its kinetic behavior in various environments. | ||||||
Methotrexate-methyl-d3 | 432545-63-6 | sc-218707 | 5 mg | $700.00 | 10 | |
Methotrexate-methyl-d3 engages with interleukin-1 (IL-1) through selective binding that alters receptor conformation and signaling cascades. Its unique isotopic labeling enhances tracking in metabolic studies, providing insights into molecular interactions. The compound's hydrophilic characteristics influence its diffusion rates and bioavailability, while its capacity to form hydrogen bonds contributes to its stability in complex biological matrices. This behavior underscores its role in modulating inflammatory pathways. | ||||||
Methotrexate-methyl-d3, Dimethyl Ester | 432545-60-3 | sc-218708 | 2.5 mg | $330.00 | ||
Methotrexate-methyl-d3, Dimethyl Ester exhibits distinctive interactions with interleukin-1 (IL-1) by modulating receptor dynamics and downstream signaling pathways. The incorporation of deuterium isotopes allows for precise kinetic studies, revealing its reactivity and stability in various environments. Its lipophilic nature facilitates membrane permeability, while the presence of ester groups enhances its solubility, impacting its distribution and interaction with cellular components. This compound's unique structural features contribute to its nuanced role in cellular signaling mechanisms. | ||||||
Diacerein | 13739-02-1 | sc-204717 sc-204717A | 50 mg 250 mg | $120.00 $544.00 | 2 | |
Diacerein acts as a selective inhibitor of interleukin-1, influencing its receptor binding and subsequent signaling cascades. Its unique structure allows for specific interactions with the IL-1 receptor, altering conformational dynamics and modulating inflammatory responses. The compound's ability to penetrate cellular membranes is enhanced by its hydrophobic characteristics, while its stability in physiological conditions supports prolonged activity. These properties underscore its intricate role in cellular communication and modulation. | ||||||
Nilvadipine | 75530-68-6 | sc-215567 | 50 mg | $177.00 | 1 | |
Nilvadipine exhibits unique interactions with interleukin-1, influencing its signaling pathways through selective receptor modulation. Its distinct molecular architecture facilitates specific binding, altering receptor conformation and downstream effects. The compound's lipophilic nature enhances membrane permeability, allowing for efficient cellular uptake. Additionally, its kinetic profile suggests a sustained interaction with target sites, contributing to its nuanced role in cellular signaling and inflammatory modulation. | ||||||