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Nilvadipine (CAS 75530-68-6)

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Alternate Names:
2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl 5-(1-Methylethyl) Ester
Application:
Nilvadipine is a potent calcium channel protein inhibitor and blocker
CAS Number:
75530-68-6
Purity:
≥98%
Molecular Weight:
385.37
Molecular Formula:
C19H19N3O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Nilvadipine is a potent calcium channel protein inhibitor and blocker (IC50 = 0.03 nM).


Nilvadipine (CAS 75530-68-6) References

Gross, G.J., et al.: Gen. Pharmacol., 14, 677 (1983), Molyvdas, P.A. and Sperelakis, N.: J. Cardiovasc. Pharmacol., 8, 449 (1986), Mizuno, K., et al.: Res. Comm. Chem. Pathol. Pharmacol., 52, 3 (1986)

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Nilvadipine, 50 mg

sc-215567
50 mg
$177.00

What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. The compound, sc-215567, is provided as a yellow crystalline powder. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
Answered by: Tech Service 8
Date published: 2017-02-09
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Rated 5 out of 5 by from Paris et alParis et al. (PubMed ID 25331948) found that nilvadipine inhibited A production and improved the clearance of A across the blood-brain barrier via spleen tyrosine kinase (Syk) inhibition located on Alzheimer's disease relevant epitopes on transgenic mice. -SCBT Publication Review -SCBT Publication Review
Date published: 2015-01-05
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Nilvadipine is rated 5.0 out of 5 by 1.
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