IGSF3 Activators
Chemicals classified as IGSF3 Activators are compounds that influence various cellular signaling pathways and adhesion processes, which could indirectly impact the function or expression of IGSF3. The mechanisms by which these chemicals act are diverse, reflecting the complex interplay of signal transduction and cellular adhesion in which IGSF3 may be involved.
Compounds like Forskolin and PMA act by activating key kinases within cells-PKA and PKC, respectively-leading to cascading effects on other enzymes and substrates that govern cell adhesion, where IGSF3 may play a role. Similarly, natural compounds like EGCG can modulate signaling pathways that influence cell adhesion, providing indirect routes for the activation of IGSF3. On the other hand, LY294002 and SB203580 work by inhibiting specific kinases, PI3K and p38 MAPK, which are central to multiple signaling pathways, including those that could engage IGSF3.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylate cyclase, raising intracellular cAMP levels, which can enhance protein kinase A (PKA) activity. PKA phosphorylation can modulate cell adhesion dynamics, potentially affecting IGSF3. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates protein kinase C (PKC), which is involved in signal transduction and could influence cell adhesion and membrane-associated proteins including IGSF3. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
A catechin found in green tea that has been shown to influence cell signaling and adhesion pathways, potentially affecting proteins like IGSF3. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
A ROCK inhibitor that influences cell shape and motility through effects on the actin cytoskeleton, potentially implicating IGSF3 in these processes. | ||||||
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $179.00 $307.00 $455.00 $924.00 $1689.00 | 7 | |
Inhibits myosin II ATPase activity, affecting cell contraction and adhesion, which could indirectly influence the function of membrane proteins such as IGSF3. | ||||||
W-7 | 61714-27-0 | sc-201501 sc-201501A sc-201501B | 50 mg 100 mg 1 g | $163.00 $300.00 $1642.00 | 18 | |
A calmodulin antagonist, which by affecting calcium signaling can have consequences on cell adhesion processes, potentially affecting IGSF3. | ||||||