IgG1 inhibitors belong to a specific chemical class that is characterized by its ability to target and interact with the immunoglobulin G subclass 1 (IgG1) antibodies. IgG1 is a crucial component of the immune system, responsible for recognizing and binding to foreign substances, thereby triggering immune responses to neutralize or eliminate them. The inhibitors designed within this chemical class are engineered to interfere with the normal function of IgG1 by obstructing its binding capacity or blocking key interactions with other immune molecules.These inhibitors are carefully developed using advanced bioengineering and molecular techniques to ensure their specificity and efficacy in inhibiting IgG1 activity.
They may work through different mechanisms, such as blocking specific binding sites on the IgG1 molecule or interrupting signaling pathways essential for its immune response activation. By doing so, IgG1 inhibitors may play a role in modulating immune responses or controlling aberrant immune reactions in certain contexts. Researchers and scientists are continually investigating the potential applications of IgG1 inhibitors, primarily in research settings, to gain insights into the complex mechanisms of the immune system and how it responds to various challenges. The detailed understanding of these inhibitors and their interactions with IgG1 can lead to valuable discoveries and insights into immune-related conditions and diseases.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Mycophenolate mofetil | 128794-94-5 | sc-200971 sc-200971A | 20 mg 100 mg | $36.00 $107.00 | 1 | |
Inhibits inosine monophosphate dehydrogenase, leading to reduced proliferation of B-cells and thus lower IgG1 levels. | ||||||
hydroxychloroquine | 118-42-3 | sc-507426 | 5 g | $56.00 | 1 | |
Can modulate immune activity and may reduce B-cell antibody production. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Similar to hydroxychloroquine, it can modulate immune system activity. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
Inhibits dihydrofolate reductase, leading to reduced B-cell proliferation and antibody production. | ||||||
Azathioprine | 446-86-6 | sc-210853D sc-210853 sc-210853A sc-210853B sc-210853C | 500 mg 1 g 2 g 5 g 10 g | $199.00 $173.00 $342.00 $495.00 $690.00 | 1 | |
Antimetabolite that affects purine synthesis, reducing B-cell proliferation and antibody production. | ||||||
FTY720 | 162359-56-0 | sc-202161 sc-202161A sc-202161B | 1 mg 5 mg 25 mg | $32.00 $75.00 $118.00 | 14 | |
Sphingosine 1-phosphate receptor modulator, sequestering lymphocytes and reducing antibody production. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Proteasome inhibitor that can affect plasma cell survival, indirectly reducing antibody levels including IgG1. | ||||||