The chemical class referred to as HYPB inhibitors comprises a diverse group of compounds that have demonstrated the ability to modulate the activity of the Huntingtin Yeast Partner B (HYPB) protein. HYPB is associated with various cellular processes and has been implicated in the context of certain neurodegenerative conditions. These inhibitors interact with specific binding sites or functional domains within the HYPB protein, effectively altering its normal function. They often exert their inhibitory effects through mechanisms that interfere with HYPB's molecular interactions or disrupt its enzymatic activity. Structurally, HYPB inhibitors can vary widely, encompassing small organic molecules, peptides, and natural products. Their inhibitory potential may stem from their ability to competitively or allosterically hinder the normal interactions of HYPB with its native binding partners or substrates.
Researchers have identified and characterized these inhibitors using a combination of molecular biology techniques, biochemical assays, and computational modeling. Understanding the properties and mechanisms of HYPB inhibitors offers valuable insights into the complex molecular pathways involving HYPB and its roles within cellular processes, providing a foundation for potential future research endeavors.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sodium phenylbutyrate | 1716-12-7 | sc-200652 sc-200652A sc-200652B sc-200652C sc-200652D | 1 g 10 g 100 g 1 kg 10 kg | $77.00 $166.00 $622.00 $5004.00 $32783.00 | 43 | |
This compound has been investigated for its potential to reduce mutant huntingtin aggregation and is thought to exert its effects partly through HYPB inhibition. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Similar to sodium phenylbutyrate, sodium butyrate has been studied for its role in inhibiting HYPB and its potential therapeutic effects in Huntington's disease. | ||||||
Cystamine dihydrochloride | 56-17-7 | sc-217990 sc-217990A | 25 g 100 g | $39.00 $105.00 | ||
Cystamine is a compound that has been explored for its potential to inhibit HYPB and modulate the progression of Huntington's disease. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, a natural compound found in turmeric, has exhibited HYPB inhibitory effects and has been studied for its neuroprotective properties in various neurodegenerative diseases, including Huntington's. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $71.00 $184.00 | 1 | |
CoQ10 has been investigated for its potential to modulate HYPB activity and mitigate the effects of oxidative stress in Huntington's disease. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium has been investigated for its ability to inhibit HYPB and its potential neuroprotective effects in Huntington's disease. | ||||||