HS6ST2 Activators
HS6ST2 Activators encompass a range of chemical compounds that facilitate the enhancement of HS6ST2's enzymatic function. Sodium Chloride and Magnesium Sulfate play pivotal roles in maintaining ionic balance and enzymatic structure, crucial for the optimal activity of HS6ST2. The presence of essential cofactors like Magnesium, Zinc from Zinc Acetate, and Manganese from Manganese(II) sulfate is fundamental for the activation of HS6ST2, as these ions can stabilize the enzyme and enhance its catalytic efficiency. Additionally, Copper(II) sulfate may contribute to the indirect enhancement of HS6ST2 by possibly improving substrate interactions. Adenosine Triphosphate (ATP) and Phosphoadenosine Phosphosulfate (PAPS) are directly involved in the sulfation process that HS6ST2 catalyzes, with ATP supplying the necessary phosphate groups and PAPS serving as the sulfate group donor, thereby directly increasing HS6ST2's functional activity.
Furthermore, compounds like Nicotinamide adenine dinucleotide (NAD+) and Acetyl-Coenzyme A are integral to the metabolic processes within the cell, which could indirectly support the energy-dependent reactions that HS6ST2 mediates. Uridine Diphosphate (UDP) is a component of PAPS, and its availability is crucial for the synthesis of thissulfate donor, consequently enhancing the efficiency of HS6ST2-mediated sulfation. The buffering capacity of Tris(hydroxymethyl)aminomethane ensures that the enzymatic environment is optimal for HS6ST2, which is sensitive to pH fluctuations. Lastly, Ammonium Sulfate contributes to the pool of sulfate ions necessary for PAPS synthesis, thereby supporting the sulfotransferase activity of HS6ST2, while the provision of acetyl groups by Acetyl-Coenzyme A may facilitate post-translational modifications that stabilize and promote HS6ST2 activity.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sodium Chloride | 7647-14-5 | sc-203274 sc-203274A sc-203274B sc-203274C | 500 g 2 kg 5 kg 10 kg | $19.00 $30.00 $60.00 $110.00 | 15 | |
As HS6ST2 is involved in sulfate conjugation processes, Sodium Chloride can provide chloride ions that enhance ionic balance for enzymatic activity, indirectly enhancing HS6ST2 function. | ||||||
Magnesium sulfate anhydrous | 7487-88-9 | sc-211764 sc-211764A sc-211764B sc-211764C sc-211764D | 500 g 1 kg 2.5 kg 5 kg 10 kg | $46.00 $69.00 $163.00 $245.00 $418.00 | 3 | |
Magnesium ions are cofactors for many enzymes; Magnesium Sulfate can stabilize the structure of proteins and enzymes, potentially enhancing the sulfotransferase activity of HS6ST2. | ||||||
Adenosine 5′-Triphosphate, disodium salt | 987-65-5 | sc-202040 sc-202040A | 1 g 5 g | $39.00 $75.00 | 9 | |
ATP provides the phosphate groups for sulfuryl transfer reactions. Adequate levels of ATP are essential for HS6ST2 enzymatic activity since it acts as a donor molecule in the sulfation process. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc ions are known to play a structural and catalytic role in many enzymes. Zinc Acetate can provide zinc which may serve as a cofactor for HS6ST2, improving its functional activity. | ||||||
Manganese(II) sulfate monohydrate | 10034-96-5 | sc-203130 sc-203130A | 100 g 500 g | $41.00 $107.00 | ||
Manganese ions act as cofactors for various enzymes, potentially enhancing the catalytic efficiency of HS6ST2 by stabilizing reactive intermediates during the sulfation process. | ||||||
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $46.00 $122.00 $189.00 | 3 | |
Copper ions can interact with protein motifs to facilitate enzyme catalysis. Copper(II) sulfate may indirectly enhance HS6ST2 activity by stabilizing its structure or interacting with substrates. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $57.00 $191.00 $302.00 $450.00 $1800.00 $3570.00 $10710.00 | 4 | |
As an essential coenzyme in redox reactions, NAD+ may enhance the overall cellular metabolism, indirectly supporting the energy-dependent sulfotransferase activity of HS6ST2. | ||||||
Uridine 5′-diphosphate sodium salt | 21931-53-3 | sc-222401 sc-222401A | 25 mg 100 mg | $38.00 $79.00 | ||
UDP forms part of the PAPS structure, which is used by HS6ST2 as a sulfate group donor. Availability of UDP may therefore enhance the synthesis of PAPS and subsequently, HS6ST2 activity. | ||||||
Ammonium Sulfate | 7783-20-2 | sc-29085A sc-29085 sc-29085B sc-29085C sc-29085D sc-29085E | 500 g 1 kg 2 kg 5 kg 10 kg 22.95 kg | $11.00 $21.00 $31.00 $41.00 $61.00 $102.00 | 9 | |
Providing sulfate ions needed for the synthesis of PAPS, Ammonium Sulfate can support the HS6ST2 sulfation process by ensuring a consistent supply of the substrate. | ||||||
Acetyl coenzyme A trisodium salt | 102029-73-2 | sc-210745 sc-210745A sc-210745B | 1 mg 5 mg 1 g | $47.00 $92.00 $5826.00 | 3 | |
Acetyl-CoA is central to metabolism and may support HS6ST2 indirectly by providing acetyl groups necessary for post-translational modifications that could enhance HS6ST2 stability and activity. | ||||||