Date published: 2026-1-9

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HPS-1 Activators

HPS-1, integral to the pathogenesis of Hermansky-Pudlak Syndrome, plays a role in the biogenesis and function of lysosome-related organelles. The direct chemical activators of HPS-1 are not well-established due to its specific role in organelle formation. However, compounds that indirectly enhance cellular processes and organelle health offer potential routes for modulation. MSH analogs and Forskolin, which stimulate melanogenesis and increase cAMP levels respectively, might indirectly support melanosomes and other organelles where HPS-1 is involved. Curcumin and N-acetylcysteine (NAC), known for their broad cellular effects and antioxidant properties, could create a favorable cellular environment for organelle function, indirectly benefiting HPS-1.

Vitamin D, with its role in various cellular processes, and Omega-3 Fatty Acids, known for their anti-inflammatory effects, might also support cellular health in a way that benefits HPS-1. Growth factors like FGF and EGF, which stimulate cell growth, could enhance organelle biogenesis and function, potentially impacting HPS-1. Additionally, compounds like Erythropoietin, IGF-1, and Creatine, though known for their roles in other cellular processes, could indirectly support the health and function of organelles relevant to HPS-1. EGCG and Resveratrol, with their varied biological activities, might also contribute to maintaining a healthy cellular environment conducive to HPS-1's role.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

By increasing cAMP levels, it may enhance cellular processes, including those related to vesicle formation and function, indirectly benefiting HPS-1.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$71.00
$163.00
$296.00
2
(1)

Involved in various cellular processes, it might positively influence organelle function and health, indirectly benefiting HPS-1.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Known for its broad cellular effects, it may positively influence melanosome formation and function, indirectly benefiting HPS-1.

N-Acetyl-L-cysteine

616-91-1sc-202232
sc-202232A
sc-202232C
sc-202232B
5 g
25 g
1 kg
100 g
$34.00
$74.00
$270.00
$114.00
34
(1)

As an antioxidant, it may support cellular health and processes related to organelle function, potentially benefiting HPS-1.

Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic Acid (22:6, n-3)

6217-54-5sc-200768
sc-200768A
sc-200768B
sc-200768C
sc-200768D
100 mg
1 g
10 g
50 g
100 g
$94.00
$210.00
$1779.00
$8021.00
$16657.00
11
(1)

Known for their anti-inflammatory effects, they might support cellular health in a way that benefits HPS-1 function.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

A component of green tea, it has various biological effects that might support organelle function, indirectly benefiting HPS-1.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Known for its antioxidant properties, it might support cellular health and organelle function, indirectly benefiting HPS-1.

Creatine, anhydrous

57-00-1sc-214774
sc-214774A
10 mg
50 g
$28.00
$79.00
2
(0)

While primarily known for its role in muscle and energy metabolism, creatine may support overall cellular health, potentially benefiting HPS-1.