HoxB6 activators belong to a class of chemical compounds designed to modulate the activity of HoxB6, a member of the Hox gene family. Hox genes are a group of developmental genes that play a fundamental role in orchestrating the body plan and segmental identity during embryogenesis. These genes are highly conserved across various species and are essential for the proper patterning of tissues and organs along the anterior-posterior axis of the developing embryo. HoxB6, in particular, is crucial for the specification and formation of structures in the vertebral column and posterior hindbrain.
HoxB6 activators are engineered to interact with HoxB6 and potentially influence its transcriptional activity. By targeting HoxB6, these compounds may modulate the expression of downstream genes involved in vertebral column development and hindbrain patterning, ultimately impacting the formation of these structures during embryonic development. Research on HoxB6 activators provides insights into the complex regulatory networks governing embryogenesis and the role of Hox genes in shaping the body plan of organisms. Understanding the molecular interactions between HoxB6 and its activators is crucial for deciphering the intricate processes that underlie early development and the establishment of proper anatomical structures. Further investigation is necessary to elucidate the precise mechanisms of action and potential biological consequences associated with HoxB6 activation, contributing to our knowledge of developmental biology and embryogenesis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid is involved in body axis patterning during embryonic development and can regulate the expression of Hox genes. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
This hormone can influence gene expression through its interaction with estrogen receptors, potentially affecting HoxB6. | ||||||
Folic Acid | 59-30-3 | sc-204758 | 10 g | $72.00 | 2 | |
Folic acid is essential for DNA methylation, a process that can control gene expression, including that of HoxB6. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Vitamin D3, through its nuclear receptor, can modulate gene expression and may impact HoxB6 expression patterns. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
As an HDAC inhibitor, sodium butyrate alters histone acetylation, potentially influencing HoxB6 expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
This compound is also an HDAC inhibitor, which can affect chromatin remodeling and gene expression, including HoxB6. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Known to affect gene expression by inhibiting HDACs, valproic acid could potentially modify HoxB6 expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
As a glucocorticoid, dexamethasone can modulate gene expression and may influence the expression of HoxB6. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium can modulate several signaling pathways, including Wnt signaling, which may affect Hox gene expression. | ||||||