Date published: 2025-12-8

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HoxB6 Activators

HoxB6 activators belong to a class of chemical compounds designed to modulate the activity of HoxB6, a member of the Hox gene family. Hox genes are a group of developmental genes that play a fundamental role in orchestrating the body plan and segmental identity during embryogenesis. These genes are highly conserved across various species and are essential for the proper patterning of tissues and organs along the anterior-posterior axis of the developing embryo. HoxB6, in particular, is crucial for the specification and formation of structures in the vertebral column and posterior hindbrain.

HoxB6 activators are engineered to interact with HoxB6 and potentially influence its transcriptional activity. By targeting HoxB6, these compounds may modulate the expression of downstream genes involved in vertebral column development and hindbrain patterning, ultimately impacting the formation of these structures during embryonic development. Research on HoxB6 activators provides insights into the complex regulatory networks governing embryogenesis and the role of Hox genes in shaping the body plan of organisms. Understanding the molecular interactions between HoxB6 and its activators is crucial for deciphering the intricate processes that underlie early development and the establishment of proper anatomical structures. Further investigation is necessary to elucidate the precise mechanisms of action and potential biological consequences associated with HoxB6 activation, contributing to our knowledge of developmental biology and embryogenesis.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Retinoic acid is involved in body axis patterning during embryonic development and can regulate the expression of Hox genes.

β-Estradiol

50-28-2sc-204431
sc-204431A
500 mg
5 g
$62.00
$178.00
8
(1)

This hormone can influence gene expression through its interaction with estrogen receptors, potentially affecting HoxB6.

Folic Acid

59-30-3sc-204758
10 g
$72.00
2
(1)

Folic acid is essential for DNA methylation, a process that can control gene expression, including that of HoxB6.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$70.00
$160.00
$290.00
2
(1)

Vitamin D3, through its nuclear receptor, can modulate gene expression and may impact HoxB6 expression patterns.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
19
(3)

As an HDAC inhibitor, sodium butyrate alters histone acetylation, potentially influencing HoxB6 expression.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

This compound is also an HDAC inhibitor, which can affect chromatin remodeling and gene expression, including HoxB6.

Valproic Acid

99-66-1sc-213144
10 g
$85.00
9
(1)

Known to affect gene expression by inhibiting HDACs, valproic acid could potentially modify HoxB6 expression.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$76.00
$82.00
$367.00
36
(1)

As a glucocorticoid, dexamethasone can modulate gene expression and may influence the expression of HoxB6.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium can modulate several signaling pathways, including Wnt signaling, which may affect Hox gene expression.