hnRNP A2/B1 inhibitors belong to a chemical class of compounds designed to interact with and modulate the activity of heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNP A2/B1) proteins. hnRNP A2/B1 is a multifunctional RNA-binding protein involved in various aspects of RNA metabolism, including splicing, transport, stability, and translation. These inhibitors are designed to interfere with the binding of hnRNP A2/B1 to RNA molecules, disrupting its role in regulating RNA processing and function.
By targeting hnRNP A2/B1, these inhibitors provide researchers with a tool to explore the complex regulatory mechanisms of RNA processing and gene expression. By perturbing hnRNP A2/B1-RNA interactions, scientists can investigate the impact on alternative splicing patterns, mRNA stability, and translational control. Additionally, studying the effects of hnRNP A2/B1 inhibitors may shed light on the roles of this protein in various cellular processes, including cell differentiation, stress responses, and tumorigenesis. Overall, hnRNP A2/B1 inhibitors offer a means to dissect the intricate roles of hnRNP A2/B1 in RNA-related pathways and to unravel its contributions to cellular functions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Kinetin | 525-79-1 | sc-207780 sc-207780A | 1 g 5 g | $38.00 $48.00 | ||
Inhibits hnRNP A2/B1 binding to RNA, altering its regulatory function. | ||||||
Erythromycin | 114-07-8 | sc-204742 sc-204742A sc-204742B sc-204742C | 5 g 25 g 100 g 1 kg | $57.00 $245.00 $831.00 $1331.00 | 4 | |
Impairs hnRNP A2/B1-dependent splicing by affecting RNA-protein interaction. | ||||||
Siomycin A | 12656-09-6 | sc-202339 sc-202339-CW sc-202339A sc-202339B | 500 µg 500 µg 2.5 mg 25 mg | $450.00 $500.00 $1350.00 $10404.00 | 4 | |
Binds to hnRNP A2/B1, modulating its involvement in RNA metabolism. | ||||||
Celastrol, Celastrus scandens | 34157-83-0 | sc-202534 | 10 mg | $158.00 | 6 | |
Reduces hnRNP A2/B1 expression and influences its RNA-binding activity. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $275.00 $474.00 $1639.00 $2497.00 $5344.00 | 4 | |
Inhibits hnRNP A2/B1 binding to RNA, affecting its splicing function. | ||||||
Fasentin | 392721-37-8 | sc-215012 sc-215012A | 5 mg 25 mg | $128.00 $449.00 | ||
Disrupts hnRNP A2/B1 interaction with RNA, altering its regulatory role. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $39.00 $59.00 $104.00 $206.00 | 8 | |
Interferes with hnRNP A2/B1 binding to RNA, impacting its function. | ||||||
E7820 | 289483-69-8 | sc-507333 | 10 mg | $102.00 | ||
Inhibits hnRNP A2/B1 phosphorylation, affecting its RNA-binding capacity. | ||||||