Date published: 2025-9-11

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hnRNP A2/B1 Activators

Common hnRNP A2/B1 Activators include, but are not limited to Sodium Butyrate CAS 156-54-7, Trichostatin A CAS 58880-19-6, Valproic Acid CAS 99-66-1, Resveratrol CAS 501-36-0 and Curcumin CAS 458-37-7.

Heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNP A2/B1) is involved in various aspects of mRNA processing and transport. Dysregulation of hnRNP A2/B1 has been linked to various pathological conditions, including cancer and neurodegenerative disorders. hnRNP A2/B1 Activators belong to a chemical class that interacts with and influences the function of heterogeneous nuclear ribonucleoproteins A2 (hnRNP A2) and B1 (hnRNP B1). These proteins are part of the hnRNP family, which plays a crucial role in regulating pre-mRNA splicing, RNA processing, and gene expression. By modulating the activity of hnRNP A2/B1, these activators impact various cellular processes at the molecular level.

Heterogeneous nuclear ribonucleoproteins (hnRNPs) are essential components of the cell's machinery for processing RNA molecules. hnRNP A2/B1 Activators may influence the binding, localization, or post-translational modifications of hnRNP A2 and B1, which can, in turn, affect their roles in RNA metabolism. Understanding the effects of activators on these hnRNPs is critical for unraveling the intricate regulatory mechanisms governing gene expression and RNA processing within cells. Researchers are keen to explore the precise molecular interactions and cellular consequences of hnRNP A2/B1 activation, which may provide insights into fundamental biological processes and uncover new strategies for modulating gene expression and RNA processing in various contexts.

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Items 11 to 14 of 14 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Sodium (meta)arsenite

7784-46-5sc-250986
sc-250986A
100 g
1 kg
$106.00
$765.00
3
(2)

Sodium arsenite activates stress-responsive signaling pathways, promoting hnRNP A2/B1 upregulation.

4-Phenylbutyric acid

1821-12-1sc-232961
sc-232961A
sc-232961B
25 g
100 g
500 g
$52.00
$133.00
$410.00
10
(1)

PBA functions as a chemical chaperone and histone deacetylase (HDAC) inhibitor, leading to hn

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

Inhibits protein synthesis; could potentially influence hnRNP A2/B1 levels by affecting overall cellular protein turnover.

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$92.00
$209.00
33
(5)

An antimetabolite and antifolate suggested compound; could potentially influence hnRNP A2/B1 levels due to its effects on nucleotide synthesis and metabolism.