Heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNP A2/B1) is involved in various aspects of mRNA processing and transport. Dysregulation of hnRNP A2/B1 has been linked to various pathological conditions, including cancer and neurodegenerative disorders. hnRNP A2/B1 Activators belong to a chemical class that interacts with and influences the function of heterogeneous nuclear ribonucleoproteins A2 (hnRNP A2) and B1 (hnRNP B1). These proteins are part of the hnRNP family, which plays a crucial role in regulating pre-mRNA splicing, RNA processing, and gene expression. By modulating the activity of hnRNP A2/B1, these activators impact various cellular processes at the molecular level.
Heterogeneous nuclear ribonucleoproteins (hnRNPs) are essential components of the cell's machinery for processing RNA molecules. hnRNP A2/B1 Activators may influence the binding, localization, or post-translational modifications of hnRNP A2 and B1, which can, in turn, affect their roles in RNA metabolism. Understanding the effects of activators on these hnRNPs is critical for unraveling the intricate regulatory mechanisms governing gene expression and RNA processing within cells. Researchers are keen to explore the precise molecular interactions and cellular consequences of hnRNP A2/B1 activation, which may provide insights into fundamental biological processes and uncover new strategies for modulating gene expression and RNA processing in various contexts.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Sodium (meta)arsenite | 7784-46-5 | sc-250986 sc-250986A | 100 g 1 kg | $106.00 $765.00 | 3 | |
Sodium arsenite activates stress-responsive signaling pathways, promoting hnRNP A2/B1 upregulation. | ||||||
4-Phenylbutyric acid | 1821-12-1 | sc-232961 sc-232961A sc-232961B | 25 g 100 g 500 g | $52.00 $133.00 $410.00 | 10 | |
PBA functions as a chemical chaperone and histone deacetylase (HDAC) inhibitor, leading to hn | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Inhibits protein synthesis; could potentially influence hnRNP A2/B1 levels by affecting overall cellular protein turnover. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
An antimetabolite and antifolate suggested compound; could potentially influence hnRNP A2/B1 levels due to its effects on nucleotide synthesis and metabolism. |