Histamine H3 Receptor Activators
Santa Cruz Biotechnology now offers a broad range of Histamine H3 Receptor Activators. Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. The effects of histamine are mediated by a family of G protein-coupled receptors, the Histamine H1, H2, H3 and H4 Receptors. Histamine H3 Receptor Activators offered by Santa Cruz activate Histamine H3 Receptor and, in some cases, other inflammation and immune response related proteins. View detailed Histamine H3 Receptor Activator specifications, including Histamine H3 Receptor Activator CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
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Items 1 to 10 of 13 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Histamine dihydrochloride | 56-92-8 | sc-202650 sc-202650A sc-202650B | 5 g 25 g 500 g | $48.00 $191.00 $507.00 | 1 | |
Histamine dihydrochloride functions as a histamine H3 receptor agonist, exhibiting a distinct affinity for the receptor's allosteric sites. Its dual ionic and hydrogen bonding capabilities promote intricate conformational changes in the receptor, modulating neurotransmitter release. The compound's hydrophilic nature enhances its solubility, facilitating rapid diffusion across cellular membranes. Additionally, its unique steric configuration allows for selective receptor activation, influencing downstream signaling cascades. | ||||||
Immethridine dihydrobromide | 87976-03-2 | sc-203603 sc-203603A | 10 mg 50 mg | $151.00 $640.00 | ||
Immethridine dihydrobromide acts as a histamine H3 receptor modulator, characterized by its ability to engage in specific electrostatic interactions with receptor domains. This compound exhibits a unique kinetic profile, promoting rapid receptor desensitization and subsequent resensitization cycles. Its structural features enable it to stabilize receptor conformations, thereby influencing ligand binding dynamics and altering intracellular signaling pathways. The compound's solubility properties further enhance its interaction with lipid bilayers, facilitating effective receptor engagement. | ||||||
R(−)-α-Methylhistamine•2HBr | 868698-49-1 | sc-471364 | 10 mg | $165.00 | ||
This chemical acts as a potent and selective agonist for the Histamine H3 Receptor, leading to receptor activation. | ||||||
Imetit dihydrobromide | 32385-58-3 | sc-203602 | 10 mg | $112.00 | ||
Imetit dihydrobromide is a highly selective Histamine H3 agonist, known for its efficacy in activating this receptor. | ||||||
Immepip dihydrobromide | 164391-47-3 | sc-204010 sc-204010A | 10 mg 50 mg | $155.00 $615.00 | ||
Immepip dihydrobromide functions as a histamine H3 receptor antagonist, distinguished by its selective binding affinity that alters receptor conformational states. This compound exhibits unique allosteric modulation, impacting downstream signaling cascades. Its interaction with the receptor is characterized by specific hydrogen bonding and hydrophobic interactions, which enhance its stability in biological membranes. Additionally, its dynamic solubility profile allows for efficient membrane permeability, influencing receptor accessibility and activity. | ||||||
Ciproxifan maleate | 184025-19-2 | sc-252608 | 5 mg | $149.00 | ||
Ciproxifan is a potent histamine H3 inverse agonist. While inverse agonists typically reduce receptor activity, in some systems, they can lead to indirect activation of downstream pathways. | ||||||
N-Methyl-1H-imidazole-4-ethanamine dihydrochloride | 16503-22-3 | sc-203638 sc-203638A | 10 mg 50 mg | $107.00 $411.00 | ||
N-Methyl-1H-imidazole-4-ethanamine dihydrochloride acts as a histamine H3 receptor antagonist, showcasing a remarkable ability to disrupt receptor-ligand interactions. Its structural features facilitate unique electrostatic interactions, promoting receptor desensitization. The compound's kinetic profile reveals rapid binding and dissociation rates, which may influence receptor turnover. Furthermore, its solvation characteristics enhance its distribution in aqueous environments, optimizing its interaction with target sites. | ||||||
Methimepip dihydrobromide | 151070-80-3 | sc-204080 sc-204080A | 10 mg 50 mg | $155.00 $670.00 | 1 | |
Methimepip dihydrobromide functions as a histamine H3 receptor antagonist, characterized by its ability to modulate neurotransmitter release through competitive inhibition. Its unique structural conformation allows for specific hydrogen bonding and hydrophobic interactions with the receptor, enhancing selectivity. The compound exhibits a favorable pharmacokinetic profile, with a balance of lipophilicity and solubility that supports effective receptor engagement and modulation of signaling pathways. | ||||||
(+)-α-Methylhistamine dihydrobromide | 75614-93-6 | sc-204426 sc-204426A | 10 mg 50 mg | $119.00 $510.00 | ||
(+)-α-Methylhistamine dihydrobromide acts as a potent histamine H3 receptor agonist, influencing neurotransmission by promoting receptor activation. Its stereochemistry facilitates precise interactions with the receptor's binding site, leading to conformational changes that enhance signal transduction. The compound's unique electronic properties contribute to its affinity, allowing for rapid receptor engagement and modulation of intracellular pathways, ultimately affecting synaptic plasticity and neurotransmitter dynamics. | ||||||
R(−)-α-Methylhistamine Dihydrochloride | 75614-89-0 | sc-208217 | 100 mg | $460.00 | ||
R(-)-α-Methylhistamine Dihydrochloride serves as a selective agonist for the histamine H3 receptor, exhibiting unique stereochemical properties that enhance its binding affinity. This compound engages in specific hydrogen bonding and hydrophobic interactions within the receptor's active site, promoting distinct conformational shifts. Its kinetic profile allows for swift receptor activation, influencing downstream signaling cascades and modulating neuronal excitability and synaptic transmission dynamics. | ||||||