Date published: 2025-10-26

1-800-457-3801

SCBT Portrait Logo
Seach Input

HIF-1 alpha Inhibitors

Santa Cruz Biotechnology now offers a broad range of HIF-1 alpha Inhibitors for use in various applications. HIF-1 alpha Inhibitors are essential tools for studying the function and regulation of hypoxia-inducible factor 1-alpha (HIF-1α), a transcription factor that plays a crucial role in cellular responses to low oxygen levels. These inhibitors help explain the role of HIF-1α in processes such as erythropoiesis. Researchers employ HIF-1 alpha Inhibitors to study the molecular mechanisms by which HIF-1α influences cell survival, proliferation, and differentiation under hypoxic conditions. Additionally, HIF-1 alpha Inhibitors are valuable in high-throughput screening assays aimed at identifying new modulators of HIF-1α activity, aiding in the discovery of novel regulatory pathways and potential research targets. The use of HIF-1 alpha Inhibitors supports the development of experimental models to dissect the complex interactions between HIF-1α and other signaling molecules, enhancing our understanding of cellular adaptation to hypoxia. By enabling precise control over HIF-1α activity, these inhibitors facilitate detailed studies of HIF-1α's role in cellular physiology. View detailed information on our available HIF-1 alpha Inhibitors by clicking on the product name.

Items 11 to 16 of 16 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Quinomycin A

512-64-1sc-202306
1 mg
$163.00
4
(1)

Quinomycin A binds to HIF-1α and inhibits its interaction with DNA, effectively reducing the expression of HIF-1α target genes.

Doxycycline-d6

564-25-0 unlabeledsc-218274
1 mg
$16500.00
(0)

In addition to its antibiotic properties, Doxycycline can inhibit HIF-1α by blocking its translation and reducing its overall levels.

Pyrvinium Pamoate

3546-41-6sc-476920A
sc-476920
250 mg
500 mg
$224.00
$414.00
(0)

Originally an anthelmintic drug, Pyrvinium Pamoate has been shown to inhibit HIF-1α by disrupting its interaction with the protein chaperone HSP90.

2-Methoxyestradiol

362-07-2sc-201371
sc-201371A
10 mg
50 mg
$70.00
$282.00
6
(1)

This natural metabolite of estrogen inhibits HIF-1α by disrupting its translation and decreasing its stability.

Chetomin

1403-36-7sc-202535
sc-202535A
1 mg
5 mg
$182.00
$661.00
10
(1)

Chetomin inhibits HIF-1α by interfering with the binding of its transcriptional coactivator p300 to the HIF-1α C-terminal activation domain.

N,N′-(Dithiodi-2,1-ethanediyl)bis[2,5-dichloro-benzenesulfonamide

927822-86-4sc-497219
25 mg
$330.00
(0)

This compound inhibits HIF-1α by disrupting its interaction with the transcriptional coactivator CBP/p300.